Skip to main content
Log in

Clinical evaluation of the fetus and neonate

Relation between intra-partum cardiotocography, Apgar score, cord blood acid-base status and neonatal morbidity

  • Originals
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Summary

The relation between intra-partum cardiotocography (CTG), cord blood acid-base status, Apgar score and neonatal morbidity was studied in 1228 consecutively live-born babies and in a subgroup of 200 babies (148 babies with a 1 min Apgar score≤8 and 52 randomly selected babies with a 1 min Apgar score≥9). The scores for the individual components of the 1 min Apgar score were strongly associated with each other, whereas the scores for the individual components of the 5 min Apgar score were less strongly associated. At 1 min the scores for muscle tone, reflex irritability and respiration but not the scores for heart rate and skin colour were associated with arterial and venous cord blood pH (low scores being associated with low pH). Out of the individual components of the Apgar score, heart rate and reflex irritability at 1 min were the best discriminators between “healthy or relatively healthy” and “severely ill” babies. Intrapartum CTG, total Apgar score and cord blood acid-base status were only weakly related. Venous cord blood pH was the best predictor of the 1 min Apgar score. Intra-partum CTG (silent pattern), 5 min Apgar score and venous cord blood pH were the best predictors of severe neonatal morbidity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Bishop YMM, Fienberg SE, Holland PW (1975) Discrete multivariate analysis: Theory and practice. MIT Press, Cambridge, Mass

    Google Scholar 

  2. Bretscher J, Saling E (1967) pH values in the human fetus during labor. Am J Obstet Gynecol 97: 906–911

    PubMed  CAS  Google Scholar 

  3. Chamberlain G, Banks J (1974) Assessment of the Apgar score. Lancet II: 1225–1228

    Article  Google Scholar 

  4. Crawford JS, Davies P, Pearson JF (1973) Significance of the individual components of the Apgar score. Br J Anaesth 45: 148–158

    Article  PubMed  CAS  Google Scholar 

  5. Dijxhoorn MJ, Visser GHA, Touwen BCL, Huisjes HJ (1987) Apgar score, meconium and acidemia at birth in small-for-gestational age infants born at term, and their relation to neurological morbidity. Br J Obstet Gynaecol 94: 873–879

    PubMed  CAS  Google Scholar 

  6. D'Souza SW, Black P, Cadman J, Richards B (1983) Umbilical venous blood pH: a useful aid in the diagnosis of asphyxia at birth. Arch Dis Child 58: 15–19

    Article  PubMed  Google Scholar 

  7. Fienberg SE (1977) The analysis of cross-classified categorical data. MTP Press, Cambridge, Mass

    Google Scholar 

  8. Huisjes HJ, Aarnoudse JG (1979) Arterial or venous umbilical pH as a measure of neonatal morbidity? Early Hum Dev 3: 155–161

    Article  PubMed  CAS  Google Scholar 

  9. Josten BE, Johnson TRB, Nelson JP (1987) Umbilical cord blood pH and Apgar scores as an index of neonatal health. Am J Obstet Gynecol 157: 843–848

    PubMed  CAS  Google Scholar 

  10. Lagerkrantz H (1982) Letter. Lancet I: 966

    Google Scholar 

  11. Lievaart M, de Jong PA (1984) Acid-base equilibrium in umbilical cord blood and time of cord clamping. Obstet Gynecol 63: 44–47

    PubMed  CAS  Google Scholar 

  12. Low JA, Galbraith RS, Muir DW, Killen HL, Pater EA, Karchmar EJ (1983) Intrapartum fetal hypoxia: a study of long-term morbidity. Am J Obstet Gynecol 145: 129–134

    PubMed  CAS  Google Scholar 

  13. Low JA, Galbraith RS, Muir DW, Killen HL, Pater EA, Karchmar EJ (1985) The relationship between perinatal hypoxia and newborn encephalopathy. Am J Obstet Gynecol 152: 256–260

    PubMed  CAS  Google Scholar 

  14. Low JA (1988) The role of blood gas and acid base assessment in the diagnosis of intrapartum fetal asphyxia. Am J Obstet Gynecol 159: 1235–1240

    PubMed  CAS  Google Scholar 

  15. Luthy DA, Shy KK, Strickland D, Wilson J, Bennett FC, Brown ZA, Benedetti TJ (1987) Status of infants at birth and risk for adverse neonatal events and long-term sequele: a study in low birth weight infants. Am J Obstet Gynecol 157: 676–679

    PubMed  CAS  Google Scholar 

  16. Ruth VJ, Raivio KO (1988) Perinatal brain damage: predictive value of metabolic acidosis and the Apgar score. BMJ 297: 24–27

    PubMed  CAS  Google Scholar 

  17. Steer PJ, Eigbe F, Lissauer TJ, Beard RW (1979) Interrelationships among abnormal cardiotocograms in labor, meconium staining of the amniotic fluid, arterial cord blood pH and Apgar scores. Obstet Gynecol 74: 715–721

    Google Scholar 

  18. Sykes GS, Molloy PM, Johnson P, Wei Gu, Ashworth F, Stirrat GM, Turnbull AC (1982) Do Apgar scores indicate asphyxia?. Lancet I: 494–496

    Article  Google Scholar 

  19. Sykes GS, Molloy PM, Johnson P, Stirrat GM, Turnbull AC (1983) Fetal distress and the condition of newborn infants. BMJ 287: 943–945

    PubMed  CAS  Google Scholar 

  20. Thorp JA, Sampson JE, Parisi VM, Creasy RK (1989) Routine umbilical cord blood gas determinations?. Am J Obstet Gynecol 161: 600–605

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Valentin, L., Ekman, G., Isberg, P.E. et al. Clinical evaluation of the fetus and neonate. Arch Gynecol Obstet 253, 103–115 (1993). https://doi.org/10.1007/BF02768736

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02768736

Key words

Navigation