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Fetal intracranial hemorrhage due to antenatal low dose aspirin intake

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Abstract

Antenatal intake of low dose aspirin is advised 1,2 for prevention of pregnancy induced hypertension, intrauterine growth retardation and pre-term labour. Aspirin has an anticoagulant effect due to its action onCyclo-oxygenase and vitamin K dependant coagulation factors. It can readily cross the placental barrier and be a potential cause for bleeding tendency in the fetus. Fetal intracranial hemorrhage, following low dose aspirin administration in a mother and subsequent effect after delivery is being reported.

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Sasidharan, C.K., Kutty, P.M., Ajithkumar et al. Fetal intracranial hemorrhage due to antenatal low dose aspirin intake. Indian J Pediatr 68, 1071–1072 (2001). https://doi.org/10.1007/BF02722359

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