Abstract
Neopterin levels have been reported elevated in diseases with changed cellular immune response. The study reported here was designed to examine whether serum neopterin (S-neopterin) could be a marker of activity in sarcoidosis.
S-neopterin was measured by radioimmunoassay in 37 patients with inactive and 34 patients with active sarcoidosis and in 38 controls. The levels were significantly elevated in both sarcoid groups and increased in stage III compared to I and II. S-neopterin levels were significantly correlated to levels of serum angiotensin-converting enzyme (SACE) and immunoglobulins IgG and IgA. The results indicate that S-neopterin may be a marker of activity in sarcoidosis.
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Eklund, A., Blaschke, E. Elevated serum neopterin levels in sarcoidosis. Lung 164, 325–332 (1986). https://doi.org/10.1007/BF02713657
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DOI: https://doi.org/10.1007/BF02713657