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Comparison of isocaloric quantities of medium-chain tryglyceride and carbohydrate in promoting weight gain in short bowel rats

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Abstract

Weight gain was studied in short-bowel rats fed diets consisting of rat chow supplemented with isocaloric quantities of long chain triglycerides (LCT), medium-chain triglycerides (MCT) or carbohydrate. Compared with the LCT-supplemented diet, MCT supplementation did not result in a significant weight gain, while a significantly increased weight gain was obtained by the rats on a sucrose- or maltose-supplemented diet. These studies suggest that while the caloric content per gram of disaccharides is only one-half that of MCT, disaccharides were better absorbed than MCT and thus provided as good, if not a better, source of calories for short-bowel rats.

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Authors and Affiliations

  1. From the Department of Medicine, University of Minnesota Hospitals, Minneapolis, Minn.

    John Hastings MD & Michael D. Levitt MD

Authors
  1. John Hastings MD
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  2. Michael D. Levitt MD
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Additional information

Supported by United States Public Health Service Grant 5 RO1 AM13309-02 and University of Minnesota Graduate Research Grant 452-0303-4909-02.

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Hastings, J., Levitt, M.D. Comparison of isocaloric quantities of medium-chain tryglyceride and carbohydrate in promoting weight gain in short bowel rats. Digest Dis Sci 16, 135–138 (1971). https://doi.org/10.1007/BF02284449

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  • DOI: https://doi.org/10.1007/BF02284449

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