Abstract
Eye movements were recorded with electro-oculography in seven patients with rod monochromatism (RM) and five with blue-cone monochromatism (BCM). The continuous horizontal nystagmus was similar in both groups. However, three patients with BCM demonstrated an intermittent, high-frequency nystagmus, in addition to the continuous nystagmus. The most striking differences between the groups were present during monocular smooth pursuit and optokinetic tracking. Patients with RM demonstrated better tracking when targets moved in the temporal-to-nasal (T-N) direction in the visual field of the viewing eye, than when targets moved in the nasal-to-temporal (N-T) direction. The velocity of optokinetic nystagmus (OKN) increased gradually over several seconds during T-N target movement. Patients with BCM did not show a directional asymmetry or a slow build-up of OKN during monocular tracking. Differences in eye movement abnormalities can be useful in differentiating these two forms of congenital color blindness from other forms of congenital nystagmus and from each other.
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Baloh RW, Langhofer L, Honrubia V, Yee RD (1980) On-line analysis of eye movements using a digital computer. Aviat Space Environ Med 51: 563–567
Baloh RW, Yee RD, Kimm J, Honrubia V (1981) Vestibulo-ocular reflex in patients with lesions involving the vestibulocerebellum. Exp Neurol 72: 141–152
Brandt T, Dichgans J, Buchele W (1974) Motion habituation: inverted self-motion perception and optokinetic after-nystagmus. Exp Brain Res 21: 337–352
Collewijn H (1969) Optokinetic eye movements in the rabbit; input-output relations. Vision Res 9: 117–132
Dell'Osso LF, Daroff RB (1975) Congenital nystagmus waveforms and foveation strategy. Doc Ophthalmol 39: 155–182
Dell'Osso LF, Schmidt D, Daroff RB (1979) Latent, manifest latent, and congenital nystagmus. Arch Ophthalmol 97: 1877–1885
Krill A (1977) Hereditary retinal and choroidal diseases, clinical characteristics, vol 2. Harper & Row, Hagerstown, pp 359–373
Yee RD (1983) Eye movement recording as a clinical tool. Ophthalmology 90: 211–222
Yee RD, Wong EK, Baloh RW, Honrubia V (1976) A study of congenital nystagmus: waveforms. Neurology 26: 326–333
Yee RD, Baloh RW, Honrubia V (1980) Study of congenital nystagmus: optokinetic nystagmus. Br J Ophthalmol 64: 926–932
Yee RD, Baloh RW, Honrubia V (1981) Eye movement abnormalities in rod monochromacy. Ophthalmology 88: 1010–1018
Yee RD, Baloh RW, Honrubia V, Jenkins HA (1982) Pathophysiology of optokinetic nystagmus. In: Honrubia V, Brazier M (eds) Nystagmus and vertigo: clinical approaches to the patient with dizziness. Academic Press, New York, pp 251–275
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This work was supported by a research grant from the National Eye Institute (EY03707) and the Dolly Green Research Scholar Award from Research To Prevent Blindness, Inc., New York, New York (Dr. Yee); presented in part at the 5th meeting of the International Neuro-ophthalmology Society on May 15, 1984 in Antwerp, Belgium
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Yee, R.D., Farley, M.K., Bateman, J.B. et al. Eye movement abnormalities in rod monochromatism and blue-cone monochromatism. Graefe's Arch Clin Exp Ophthalmol 223, 55–59 (1985). https://doi.org/10.1007/BF02150944
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DOI: https://doi.org/10.1007/BF02150944