Summary
Enterokinase activity from rat duodenal brush borders was assayed in vitro in the presence of purified lectins from 3 leguminous seeds. Noncompetitive inhibition of the enzyme was observed in each case.Phaseolus hemagglutinin was the most potent inhibitor among the 3 lectins tested.
References
Kakade, M.L., and Evans, R.J., J. Nutr.90 (1966) 191.
Jaffé, W.G., and Vega Lette, C.L., J. Nutr.94 (1968) 203.
Pusztai, A., and Palmer, R., J. Sci. Fd Agric.28 (1977) 620.
Kakade, M.L., Hoffa, D.E., and Liener, I.E., J. Nutr.103 (1973) 1772.
Turner, R.H., and Liener, I.E., J. agric. Fd Chem.23 (1975) 484.
Pusztai, A., Clarke, E.M.W., and King, T.P., Proc. Nutr. Soc.38 (1979) 115.
Lorenzsonn, V., and Olsen, W.A., Gastroenterology82 (1982) 838.
Jaffé, W.G., in: Toxic Constituents of Plant Foodstuffs, p. 69. Ed. I. Liener, Academic Press, New York and London 1969.
Bhat, P.G., Jacob, R.T., and Pattabiraman, T.N., J. Biosci.3 (1981) 371.
Baratti, J. Maroux, S., Louvard, D., and Desnuelle, P., Biochim. biophys. Acta315 (1973) 147.
Grant, D.A.W., and Hermon-Taylor, J., Biochem. J.155 (1976) 243.
Itoh, M., Kondo, K., Komada, H., Izutsu, K., Shimbayashi, Y., and Takahashi, T., Agric. Biol. Chem.44 (1980) 125.
Nordström, C., and Dahlqvist, A., Biochim. biophys. Acta242 (1971) 209.
Erlanger, B.F., Kokowsky, N., and Cohen, W., Archs Biochem. Biophys.95 (1961) 271.
Räsänen, V., Weber, T.M., and Gräsbeck, R., Eur. J. Biochem.38 (1973) 193.
Magee, A.I., Grant, D.A.W., and Hermon-Taylor, J., Clinica chim. Acta115 (1981) 241.
Dani, M., Manca, F., and Rialdi, G., Biochim. biophys. Acta667 (1981) 108.
Weber, T.H., Experientia29 (1973) 863.
Tarlow, M.J., Hadorn, B., Arthurton, M.W., and Lloyd, J.K., Arch. Dis. Childhood45 (1970) 651.
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Rouanet, J.M., Besançon, P. & Lafont, J. Effect of lectins from leguminous seeds on rat duodenal enterokinase activity. Experientia 39, 1356–1358 (1983). https://doi.org/10.1007/BF01990102
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DOI: https://doi.org/10.1007/BF01990102