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Photodynamic effect of the porphyrin derivative meso-tetra (4-N-methylpyridyl) porphine on sister chromatid exchanges in meristematic cells

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The porphyrin derivative meso-tetra (4-N-methyl-pyridyl) porphine tetraiodide (TMpyP) was tested for its ability to induce sister chromatid exchanges (SCE) inAllium cepa roots. A significant increase in the SCE frequency was observed when BrdU-substituted chromosomes were treated with TMpyP during the G1 period of the second-division cycle and also when treatment with TMpyP was followed by blue light irradiation.

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Authors and Affiliations

  1. Departamento de Citologia e Histologia, Facultad de Ciencias, Universidad Autonoma de Madrid, E-28049, Madrid, Spain

    A. Villanueva, M. J. Hazen & J. C. Stockert

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  1. A. Villanueva
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  2. M. J. Hazen
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  3. J. C. Stockert
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Villanueva, A., Hazen, M.J. & Stockert, J.C. Photodynamic effect of the porphyrin derivative meso-tetra (4-N-methylpyridyl) porphine on sister chromatid exchanges in meristematic cells. Experientia 42, 1269–1271 (1986). https://doi.org/10.1007/BF01946418

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  • DOI: https://doi.org/10.1007/BF01946418

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