Summary
Biotin deficiency inAspergillus nidulans has been found to increase the uptake of ammonium ions, associated with a marked increase in the activity of NADP-linked glutamate dehydrogenase, which is found to be the major route of ammonia assimilation in this culture. The results obtained are discussed with respect to the growth ofAspergillus nidulans during biotin deficiency.
Similar content being viewed by others
References
K. K. Rao andV. V. Modi, Can. J. Microbiol.14, 813 (1968).
K. K. Rao andV. V. Modi, Experientia26, 590 (1970).
J. D. Desai andV. V. Modi, Can. J. Microbiol.21, 807 (1975).
J. D. Desai andV. V. Modi, Curr. Sci.44, 136 (1975).
J. D. Desai andV. V. Modi, Indian J. exp. Biol.12, 438 (1974).
H. R. Skeggs, inAnalytical Microbiology (Ed.F. Kavanagh; Academic Press Inc., New York 1963), p. 421.
K. W. Thomulka andA. G. Moat, J. Bact.109, 25 (1972).
R. J. Roon, H. L. Evan andI. Lerimorb, J. Bact.118, 89 (1974).
B. A. Fry, J. gen. Microbiol.59, 579 (1955).
O. H. Lowry, N. Y. Rosebrough, A. L. Farr andR. J. Randall, J. biol. Chem.193, 265 (1951).
A. G. Moat andF. Ahmad, Wallerstain Labs Commun.28, 111 (1965).
D. J. D. Nicholas, inThe Fungi (Eds.G. C. Ainsworth andA. S. Sussaman; Academic Press, New York/London 1965), vol. 1, p. 349.
Y. S. Halpern andH. E. Umberger, J. Bact.80, 285 (1960).
O. H. Lamminnaki andJ. R. Pierce, J. Inst. Brew.75, 515 (1969).
R. Burk andJ. Pateman, Nature, Lond.196, 450 (1962).
C. M. Brown, V. J. Burn andB. Johnson, Nature New Biol.246, 115 (1973).
L. Biggerghering, J. gen. Microbiol.13, 45 (1955).
H. Holzer, G. Hierholzer andI. Witt, Mech. Reg. Act. Cell. Microorg.124, 407 (1963).
A. Sims andB. Folker, Proc. R. Soc. London, Ser. B.159, 479 (1964).
R. Barralt andW. Stickland, Arch. Biochem. Biophys.102, 66 (1963).
J. R. Kinghorn andJ. Pateman, J. gen. Microbiol.78, 39 (1973).
Author information
Authors and Affiliations
Additional information
J. D. Desai gratefully acknowledges the receipt of a research fellowship from the Government of India, Department of Atomic Energy, Bombay.
Rights and permissions
About this article
Cite this article
Desai, J.D., Modi, V.V. Assimilation of ammonia and growth of biotin deficientAspergillus nidulans . Experientia 32, 423–424 (1976). https://doi.org/10.1007/BF01920773
Issue Date:
DOI: https://doi.org/10.1007/BF01920773