Abstract
Experiments on rabbits and in vitro showed the antiaggregation action of some new xanthine derivatives. It was shown that they also have anticoagulant activity and prevent thrombus formation.
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Literature Cited
K. M. Lakin, V. A. Fel'dbaum, V. S. Efimov, et al., in: Abstracts of Proceedings of the 12th International Congress on Blood Transfusion [in Russian], Moscow (1969), p. 251.
S. S. Liberman, R. A. Al'tshuler, and L. N. Gerchikov, Farmakol. Toksikol., No. 5, 586 (1970).
V. A. Lyusov and Yu. B. Belousov, Kardiologiya, No. 7, 50 (1970).
V. A. Lyusov and Yu. B. Belousov, Lab. Delo, No. 8, 459 (1971).
M. G. Ardlie, G. Glew, B. G. Schultz, et al., Thrombos, Diathes. Haemorrh. (Stuttgart),18, 670 (1967).
G. V. R. Born, J. Physiol. (London),162, 67P (1962).
P. F. Crosti and P. E. Lucchelli, J. Clin. Path.,15, 191 (1962).
L. Donner, Vnitrni Lék.,9, 810 (1963).
J. R. A. O'Brien, J. B. Heywood, J. A. Heady, et al., Thrombos Diathes. Haemorrh., (Stuttgart),16 752 (1966).
A. Poplawski, M. Skorulska, and S. Niewiarowski, J. Atheroscl. Res.,8, 721 (1968).
M. B. Zucker and J. Borelli, Proc. Soc. Exp. Biol. (New York),109, 779 (1962).
Additional information
Department of Pharmacology, Moscow Medical Stomatological Institute. Laboratory of Pharmacology, S. Ordzhonikidze All-Union Pharmaceutical Chemical Research Institute, Moscow. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 89, No. 2, pp. 181–182, February, 1980.
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Lakin, K.M., Ovnatanova, M.S., Matyashova, M.A. et al. Investigation of the effect of some xanthine derivatives on platelet aggregation and other indices of hemostasis. Bull Exp Biol Med 89, 159–160 (1980). https://doi.org/10.1007/BF00831008
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DOI: https://doi.org/10.1007/BF00831008