Summary
In the sural nerve of a 62-year-old woman with impaired glucose tolerance test and polyneuropathy, many intra-axonal polyglucosan bodies were observed. Polyglucosan bodies have been described in spontaneously or alloxan-diabetic rats, but are not usually observed in human diabetic neuropathy. Since intra-axonal polyglucosan bodies can occur in the sural nerve in various diseases and in aging, they are considered as non-specific changes. Their presence is probably related to a primary axonal neuropathy.
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Supported in part by CNR (Center for Cerebral Neurophysiclogy, Genova) and by CNR contract no. 83.02062.04
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Mancardl, G.L., Schenone, A., Tabaton, M. et al. Polyglucosan bodies in the sural nerve of a diabetic patient with polyneruopathy. Acta Neuropathol 66, 83–86 (1985). https://doi.org/10.1007/BF00698301
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DOI: https://doi.org/10.1007/BF00698301