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Cardiovascular and ventilatory effects of catecholamines in unrestrained eels (Anguilla anguilla L.)

A study of seasonal changes in reactivity

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Summary

The cardiovascular and ventilatory effects caused by exogenous catecholamines were completely different in winter and in summer. In winter, adrenaline and noradrenaline produced hypoventilation, bradycardia and a rise in arterial pressure whilst isoprenaline was without effect. Treatment with phentolamine showed that these cardiovascular and ventilatory effects resulted from the stimulation of α adrenoceptors only.

In contrast it was demonstrated that the hyperventilatory and tachycardiac effects observed in summer were the consequence of stimulation of β adrenoceptors. After treatment with a β blocking agent, isoprenaline did not produce any significant effect whilst adrenaline and noradrenaline caused hypoventilation and bradycardia as in winter, but to a lesser extent; these responses were abolished by an α blocking agent.

Several possible interpretations of these results are proposed in order to explain the different modes of action by which catecholamines produce the cardiovascular and ventilatory responses observed in winter on one hand and in summer on the other.

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Authors and Affiliations

  1. Laboratoire de Physiologie du Poisson, ERA CNRS 622, Faculté des Sciences, F-29283, Brest Cedex, France

    Marguerite Peyraud-Waitzenegger, Lucien Barthelemy & Claude Peyraud

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  1. Marguerite Peyraud-Waitzenegger
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  2. Lucien Barthelemy
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  3. Claude Peyraud
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Peyraud-Waitzenegger, M., Barthelemy, L. & Peyraud, C. Cardiovascular and ventilatory effects of catecholamines in unrestrained eels (Anguilla anguilla L.). J Comp Physiol B 138, 367–375 (1980). https://doi.org/10.1007/BF00691571

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