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Rabbit immunoglobulin allotype A12: A new agglutinating specificity

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Abstract

A new allotype, A12, present on rabbit IgG is described. This allotype is detected by inhibition-of-agglutination techniques similar to those employed for the previously described allotype A11. The specificity is on the H chain in the hinge region of IgG. It can be associated with any of the H chain group a allotypes. A11 and A12 are transmitted by codominant autosomal genes.

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Authors and Affiliations

  1. Department of Microbiology, University of Texas, Austin, Texas

    William J. Mandy

  2. Department of Biology, City of Hope Medical Center, Duarte, California

    Charles W. Todd

Authors
  1. William J. Mandy
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  2. Charles W. Todd
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Additional information

This work was supported by Welch Foundation Grant F 209, by grants AI 07184 and AI 07995 from the National Institute of Allergy and Infectious Diseases, and by an NIH Animal Care Grant FR 00433.

Recipient of PHS Career Development Award 1-K3-GM-21,252.

Supported by a City of Hope fund established in the name of Ralph Carson.

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Mandy, W.J., Todd, C.W. Rabbit immunoglobulin allotype A12: A new agglutinating specificity. Biochem Genet 4, 59–71 (1970). https://doi.org/10.1007/BF00484018

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  • DOI: https://doi.org/10.1007/BF00484018

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