Abstract
In a retrospective study, 1538 strains of β-haemolysin-producing Staphylococcus species isolated from dermatitis in dogs at three veterinary clinical microbiology laboratories in Norway during 1986–87 and 1993–94 were investigated for their antimicrobial susceptibility. None of the strains was resistant to cloxacillin, cephalexin or the quinolones enrofloxacin and ciprofloxacin. More than 96% of the strains were susceptible to trimethoprim-sulphonamide, bacitracin and fucidic acid. Between 67% and 89% of the strains were susceptible to erythromycin, lincosamides, tetracycline, neomycin and chloramphenicol. Only 37.9% of the strains were susceptible to penicillin. The frequency of penicillin resistance increased significantly between the first and second periods, from 46.0% to 58.6%. The frequency of resistance to lincomycin, clindamycin and erythromycin also increased significantly between the first and second periods, from 3.0%, 2.1% and 3.3% to 25.5%, 19.5% and 24.8%, respectively. A moderate increase in resistance to tetracycline was also noted, from 20.4% in the first to 27.6% in the second period. On the other hand, the frequency of resistance to trimethoprim-sulphonamide decreased significantly from 4.1% in the first to 0.9% in the second period. Many different resistance patterns were observed in each period. However, the proportion of multiresistant strains increased from 2.1% in the first to 10.2% in the second period. There was a decrease in resistance to the combination of trimethoprim-sulphonamide and penicillin from the first to the second period. Resistance to the combination of lincosamides and pencillin increased. For the combinations penicillin-tetracycline-lincosamides, pencillin-lincosamides-erythromycin, and pencillin-tetracycline-lincosamides-erythromycin, there was a striking increase in resistance between the first and the second periods.
Similar content being viewed by others
Abbreviations
- CVL:
-
Central Veterinary Laboratory
- NCVM:
-
Norwegian College of Veterinary Medicine
- NVL:
-
Norwegian Veterinary Laboratory
References
Awad-Masalmeh, M., Jurinka, A. and Willinger, H., 1988. Bakteriologische Untersuchungen zur Pyodermie des Hundes Therapeutischer Einsatz einer autogenen Vakzine. Wiener Tierarzliche Monatschrift, 75, 232–236
Casals, J.B. and Pringler, N., 1982. Antibacterial/Antifungal Sensitivity Testing Using Neo-Sensitabs, 7th edn, (Rosco Diagnostica, Taastrup, Denmark)
Casals, J.B. and Pringler, N., 1991. Antibacterial/Antifungal Sensitivity Testing Using Neo-Sensitabs, 9th edn, (Rosco Diagnostica, Taastrup, Denmark)
Cerri, D., Bizetti, M. and Balestri, L., 1984. Piodermiti del cane. Caratterizzazione di stripiti batterici isolati e loro sensibilizzazione ad alcuni antibiotici. Annali Facolta Medicina Veterinaria Pisa, 37, 129–140
Cohen, M.L., 1992. Epidemiology of drug resistance: implications for a post-antimicrobial era. Science, 257, 1050–1055
Greene, R.T. and Schwarz, S., 1992. Small antibiotic resistance plasmids in Staphylococcus intermedius. Zentralblatt fur Bakteriologie, 276, 380–389
Hirooka, E.Y., Muller, E.E., Freitas, J.C., Vicente, E., Yoshimoto, Y. and Bergdoll, M.S., 1988. Enterotoxigenicity of Staphylococcus intermedius of canine origin. International Journal of Food Microbiology, 7, 185–191
Høie, S. and Fossum, K., 1989. Antibodies to staphylococcal DNases in sera from different animal species, including humans. Journal of Clinical Microbiology, 27, 2444–2447
Junttila, J., Schildt, R. and Hintikka, E.-L., 1987. Koiran ihotulehduksista eristettyjen stafylokokkien herkkyys mikrobilääkkeille. Suomen Eläinlääkärilehti, 93, 263–267
Küng, K., Riond, J.-L. and Wanner, M., 1993. Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and oral administration of enrofloxacin in dogs. Journal of Veterinary Pharmacology and Therapeutics, 16, 462–468
Kunkle, G.A., 1987. New considerations for rational antibiotic therapy of cutaneous staphylococcal infection in the dog. Seminars in Veterinary Medicine and Surgery (Small Animal), 2, 212–220
Levy, S.B., 1992. The Antibiotic Paradox. How Miracle Drugs are Destroying the Miracle, (Plenum Press, New York)
Love, D.N., 1989. Antimicrobial susceptibility of staphylococci isolated from dogs. Australian Veterinary Practitioner, 19, 196–200
Medleau, L., Long, R.E., Brown, J. and Miller, W.H., 1986. Frequency and antimicrobial susceptibility of Staphylococcus species isolated from canine pyodermas. American Journal of Veterinary Research, 47, 229–231
Muller, E.E., de Freitas, J.C. and Alfieri, A.A., 1986. Isolamento, caracterizaçâo e susceptibilidade a antimicrobianos de estafilococos coagulase-positivos de câes com lesôes de pele, na regiâo de londrina, pr. Semina, 7, 34–37
Muller, G.H., Kirk, R.W. and Scott, D.W., 1989. Small Animal Dermatology, 4th edn, (WB Saunders, Philadelphia), 245–247
Noble, W.C. and Kent, L.E., 1992. Antibiotic resistance in Staphylococcus intermedius isolated from cases of pyoderma in the dog. Veterinary Dermatology, 3, 71–74
O'Brien, T.F., Huq, M.I., Acar, J.F., Burchall, J.J., Kleeberg, H.H., Kronvall, G., Ohashi, M., Pinto, M.E., Rowe, B., Sng, E.H., Trabulsi, L.R., Fu, W. and Wiedemann, B., 1987. Resistance of bacteria to antibacterial agents: Report of task force 2. Reviews of Infectious Diseases, 9, S244-S260
Parry, M.F., 1989. Epidemiology and mechanisms of antimicrobial resistance. American Journal of Infectious Control, 17, 286–294
Prescott, J.F. and Baggot, J.D., 1993. Antimicrobial Therapy in Veterinary Medicine, 2nd edn, (Blackwell, Boston)
Quinn, P.J., Carter, M.E., Markey, B. and Carter, G.R., 1994. Clinical Veterinary Microbiology, (Wolfe, London)
Schwarz, S., Werckenthin, C., Pinter, L., Kent, L.E. and Noble, W.C., 1995. Chloramphenicol resistance in Staphylococcus intermedius from a single veterinary centre: evidence for plasmid and chromosomal location of the resistance genes. Veterinary Microbiology, 43, 151–159
Schwarz, S., Cardoso, M., Grölz-Krug, S. and Blobel, H., 1990. Common antibiotic resistance plasmids in Staphylococcus aureus and Staphylococcus epidermidis from human and canine infections. Zentralblatt für Bakteriologie, 273, 369–377
Skaar, I. and Stenwig, H., 1990. Antibiotikaresistens hos bakterier isolert fra rutineundersøkelser i perioden 1986–1988. Norsk Veterinaertidsskrift, 102, 353–361
Statistix, 1992. User's Manual, Version 4.0. (Analytical Software, Tallahassee).
Vokoun, P., 1985. Antibiogramy nejcastejsí mikroflory pyodermií psu. Veterinarstvi, 35, 515–517
Voss, A., Milatovic, D., Wallrauch-Schwarz, C., Rosdahl, V.T. and Braveny, I., 1994. Methicillin-resistant Staphylococcus aureus in Europe. European Journal of Clinical Microbiology and Infectious Diseases, 13, 50–55
Wegener, H.C. and Pedersen, K., 1992. Variations in antibiograms and plasmid profiles among multiple isolates of Staphylococcus intermedius from pyoderma in dogs. Acta Veterinaria Scandinavica, 33, 391–394
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kruse, H., Hofshagen, M., Thoresen, S.I. et al. The antimicrobial susceptibility of Staphylococcus species isolated from canine dermatitis. Veterinary Research Communications 20, 205–214 (1996). https://doi.org/10.1007/BF00366918
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00366918