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Heritable fragile sites on human chromosomes

IV. Silver staining

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Summary

The chromosomal gaps associated with fragile sites at 2q11, 10q23, 11q13, 16q22, 20p11 and Xq27 do not stain with silver nitrate as do NOR regions of the acrocentric chromosomes.

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References

  • Bloom, S. E., Goodpasture, C.: An improved technique for selective silver staining of nucleolar organiser regions in human chromosomes. Hum. Genet. 34, 199–206 (1976)

    Google Scholar 

  • Goodpasture, C., Bloom, S. E., Hsu, T. C., Arrighi, F. E.: Human nucleolus organisers: The satellites of the stalks? Am. J. Hum. Genet. 28, 559–566 (1976)

    Google Scholar 

  • Harvey, J., Judge, C., Wiener, S.: Familial X-linked mental retardation with an X-chromosome abnormality. J. Med. Genet. 14, 46–50 (1977)

    Google Scholar 

  • Hayata, I., Oshimura, M., Sandberg, A. A.: N-Band polymorphism of human acrocentric chromosomes and its relevance to satellite association. Hum. Genet. 36, 55–61 (1977)

    Google Scholar 

  • Miller, D. A., Tantravahi, R., Dev, V. G., Miller, O. J.: Frequency of satellite association of human chromosomes is correlated with amount of Ag-staining of the nucleolus organiser region. Am. J. Hum. Genet. 29, 490–502 (1977)

    Google Scholar 

  • Neu, R. L., Ortega, C. C., Barg, G. A., Pinto, W., Gardner, L. I., Howell, W. M., Denton, T. E.: Inclusion of satellites in an 18/21 translocation chromosome shown by ammoniacalsilver staining (sat-banding) in a case of partial trisomy 18. J. Med. Genet. 13, 520–522 (1976)

    Google Scholar 

  • Oliver, N., Francke, U., Taylor, K. M.: Silver staining studies on the short arm variant of human chromosome 17. Hum. Genet. 42, 79–82 (1978)

    Google Scholar 

  • Sutherland, G. R.: Heritable fragile sites on human chromosomes I. Factors affecting expression in lymphocyte culture. Am. J. Hum. Genet. 31, 125–135 (1979a)

    Google Scholar 

  • Sutherland, G. R.: Heritable fragile sites on human chromosomes II. Distribution, phenotypic effects and cytogenetics. Am. J. Hum. Genet. 31, 136–148 (1979b)

    Google Scholar 

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Authors and Affiliations

  1. Cytogenetics Unit, Department of Histopathology, Adelaide Children's Hospital, 5006, North Adelaide, S. A., Australia

    G. R. Sutherland & P. Leonard

Authors
  1. G. R. Sutherland
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  2. P. Leonard
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Sutherland, G.R., Leonard, P. Heritable fragile sites on human chromosomes. Hum Genet 53, 29–30 (1979). https://doi.org/10.1007/BF00289446

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  • DOI: https://doi.org/10.1007/BF00289446

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