Summary
By means of a double labeling method with H3-thymidine and 5-bromodeoxyuridine, it was found that the X chromosome showed no sign of change from an allocyclic to an isocyclic state, or vice versa in 6.5- and 7.5-day mouse embryos. Thus, reversal of allocycly may not account for the predominance of cells with the paternally derived X chromosome inactive in the yolk sac and the chorion of the mouse embryo.
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Takagi, N. Stability of X chromosome differentiation in mouse embryos. Hum. Genet. 34, 207–211 (1976). https://doi.org/10.1007/BF00278890
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DOI: https://doi.org/10.1007/BF00278890