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Gc (vitamin D binding protein) subtypes in rheumatoid arthritis

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Summary

Two hundred and six patients with rheumatoid arthritis were examined for their association with the subtypes of Gc (vitamin D binding protein). In patient groups there is 11% excess of individuals with Gc*2 allele compared to the control group, giving a relative risk of 1.55. This risk increases with the humoral status of the individual. A possible physiological basis between the association of vitamin D binding protein and rheumatoid arthritis is discussed.

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Authors and Affiliations

  1. Department of Human Genetics, University of Newcastle upon Tyne, 19 Claremont Place, NE2 4AA, Newcastle upon Tyne, England

    S. S. Papiha

  2. Department of Rheumatology, Dryburn Hospital, Durham, England

    B. Pal

Authors
  1. S. S. Papiha
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  2. B. Pal
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Papiha, S.S., Pal, B. Gc (vitamin D binding protein) subtypes in rheumatoid arthritis. Hum Genet 70, 278–280 (1985). https://doi.org/10.1007/BF00273457

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  • DOI: https://doi.org/10.1007/BF00273457

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