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Altered cotransduction frequencies exhibited by HT-mutants of Salmonella-phage P22

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Summary

Phage P22-mutants with increased transduction ability (HT-mutants) show in comparison to wild type P22, different frequencies of cotransduction for markers on two different transducing fragments of the Salmonella chromosome. The data are interpreted as indicating that host DNA to be packaged is cut by HT-mutants at sites different from those cut by wild-type phage, due to an altered specificity of the nuclease responsible for this step.

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Authors and Affiliations

  1. Genetisches Institut der Universität München, München, Germany

    Horst Schmieger & Horst Backhaus

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  1. Horst Schmieger
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  2. Horst Backhaus
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Communicated by W. Maas

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Schmieger, H., Backhaus, H. Altered cotransduction frequencies exhibited by HT-mutants of Salmonella-phage P22. Molec. Gen. Genet. 143, 307–309 (1976). https://doi.org/10.1007/BF00269408

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  • DOI: https://doi.org/10.1007/BF00269408

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