Skip to main content
Log in

Surgery of large retrochiasmatic craniopharyngiomas in children

  • Original Papers
  • Published:
Child's Nervous System Aims and scope Submit manuscript

Abstract

From 1981 to 1988, 24 patients with craniopharyngiomas were operated at the Neurosurgical Clinic of the City Hospital of Hannover. Eleven patients were females and 13 males. The median age was 39 years. Ten patients were 20 years of age or younger at the time of surgery. Among these there were four patients who had large (more than 3 cm in greatest diameter), prevalently retrochiasmatic tumors. They represent 40% of the patients up to 20 years of age. Their age ranged from 8 to 17 years; they were all females. Two patients presented with increased intracranial pressure secondary to hydrocephalus, one patient with decreased vision, and one patient presented with seizures. One patient had been previously operated twice elsewhere. A preoperative shunting procedure was necessary in two patients (in one it was bilateral). All patients were preoperatively evaluated with enhanced and nonenhanced computerized tomography (CT) and with angiography. The major tumor diameter was 4 cm or more in three patients and between 3 and 4 cm in one patient. All tumors were prevalently retrochiasmatic. Three tumors extended to the level of the middle clivus. The tumor was approached subfrontally in two patients and subfrontotemporally in two patients. There was no operative mortality. No patient was neurologically worse postoperatively. All patients required hormonal replacement. Adjuvant therapy was not given. All four patients are clinically and CT recurrence free 5 and 20 months and 3 and 4 years after the surgery.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Al Mefty O, Hassoumah M, Weaver P, Sakati N, Jinkins JR, Fox JL (1985) Microsurgery for giant craniopharyngiomas in children. Neurosurgery 17:585–595

    Google Scholar 

  2. Amacher AL (1980) Craniopharyngioma. The controversy regarding radiotherapy. Child's Brain 6:57–64

    Google Scholar 

  3. Baskin DS, Wilson CB (1986) Surgical management of craniopharyngiomas. A review of 74 cases. J Neurosurg 65:22–27

    Google Scholar 

  4. Carmel PW (1985) Craniopharyngiomas. In: Wilkins RH, Rengachary SS (eds) Neurosurgery, vol 1. McGraw-Hill, New York, pp 905–916

    Google Scholar 

  5. Carmel PW, Antunes JL, Chang CH (1982) Craniopharyngiomas in children. Neurosurgery 11:382–389

    Google Scholar 

  6. Cavazzuti V, Fischer EG, Welch K, Belli JA, Winston KR (1983) Neurological and psychophysiological sequelae following different treatments of craniopharyngiomas in children. J Neurosurg 59:409–417

    Google Scholar 

  7. Ciric IS, Cozzens JW (1980) Craniopharyngiomas. Transphenoidal method of approach-for the virtuoso only? Clin Neurosurg 27:169–187

    Google Scholar 

  8. Cobb CA, Youmans JR (1982) Brain tumors of disordered elmbryogenesis in adults. In: Youmans JR (ed) Neurological surgery. A comprehensive reference guide to the diagnosis and management of neurosurgical problems, vol 5. Saunders, Philadelphia London, pp 2899–2935

    Google Scholar 

  9. Djordević M, Djordević Z, Janicijević M, Nestorović B, Stefanović B, Ivkov M (1979) Surgical treatment of craniopharyngiomas in children. Acta Neurochir (Wien) 28 [Suppl]:344–347

    Google Scholar 

  10. Fischer EG, Welch K, Belli JA, Wallman J, Shillito JJ, Winston KR, Cassady R (1985) Treatment of craniopharyngiomas in children, 1972–1981. J Neurosurg 69:496–501

    Google Scholar 

  11. Grover WD, Rorke LB (1968) Invasive craniopharyngioma. J Neurol Neurosurg Psychiatry 31:580–582

    Google Scholar 

  12. Hakuba A, Nishimura S, Inoue Y (1985) Transpetrosal-transtentorial approach and its application in the treatment of retrochiasmatic craniopharyngiomas. Surg Neurol 24:405–415

    Google Scholar 

  13. Hoffman HJ, Hendrick EB, Humphreys RP, Buncic JR, Armstrong DL, Jenkin RDT (1979) Management of craniopharyngioma in children. J Neurosurg 47:218–227

    Google Scholar 

  14. Hoffman HJ, Chuang S, Ehrlich R, Buncic R, Netley C, Hendrick EB, Humphreys RP (1985) The microsurgical removal of craniopharyngiomas in childhood. Concepts Pediatr Neurosurg 6:52–62

    Google Scholar 

  15. Katz EL (1975) Late results of radical excision of craniopharyngiomas in children. J Neurosurg 42:86–90

    Google Scholar 

  16. Laws ER Jr (1980) Transphenoidal microsurgery in the management of craniopharyngioma. J Neurosurg 52:661–666

    Google Scholar 

  17. Lyen KR, Grant DB (1982) Endocrine function, morbidity and mortality after surgery for craniopharyngioma. Arch Dis Child 57:837–841

    Google Scholar 

  18. Manaka S, Teramoto A, Takakura K (1985) The efficacy of radiotherapy for craniopharyngiomas. J Neurosurg 62:648–656

    Google Scholar 

  19. Matson DD (1969) Neurosurgery of infancy and childhood. Thomas, Springfield, Ill, pp 556–557

    Google Scholar 

  20. Mori K, Handa H, Murata T, Takeuchi J, Miwa S, Osaka K (1980) Results of treatment of craniopharyngioma. Child's Brain 6:303–312

    Google Scholar 

  21. Patterson RH Jr, Danylevich A (1980) Surgical removal of craniopharyngiomas by a transcranial approach through the lamina terminalis and sphenoid sinus. Neurosurgery 7:111–117

    Google Scholar 

  22. Pertuiset B (1975) Craniopharyngiomas. In: Vinken PJ, Bruyn GW (eds) Handbook of clinical neurology, vol 18. North-Holland, Amsterdam Oxford, pp 531–572

    Google Scholar 

  23. Raimondi AJ (1987) Pediatric neurosurgery. Theoretic principles, art of surgical techniques. Springer, New York Berlin Heidelberg, pp 282–286

    Google Scholar 

  24. Raimondi AJ, Rougerie J (1983) A critical review of personal experiences with craniopharyngioma: clinical history, surgical techniques and operative results. Concepts Pediatr Neurosurg 3:1–34

    Google Scholar 

  25. Rougerie J (1979) What can be expected from the surgical treatment of craniopharyngiomas in children. Report of 92 cases. Child's Brain 5:433–449

    Google Scholar 

  26. Rougerie J, Raimondi AJ (1983) Craniopharyngiomas. In: Amador L (ed) Brain tumors in the young. Thomas, Springfield, Ill, pp 599–621

    Google Scholar 

  27. Symon LS, Sprich W (1985) Radical excision of craniopharyngioma. Results in 20 patients. J Neurosurg 62:174–181

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ammirati, M., Samii, M. & Sephernia, A. Surgery of large retrochiasmatic craniopharyngiomas in children. Child's Nerv Syst 6, 13–17 (1990). https://doi.org/10.1007/BF00262259

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00262259

Key words

Navigation