Abstract
The first case of sebaceous gland metaplasia arising in cardiac-type mucosa of the oesophago-gastric junction of 71-year-old man is reported. Within cardiac glands, small nests composed of clear cells closely resembling sebaceous glands of the skin were found. Immunohistochemically, the cell nests stained positively for a monoclonal antibody 115D8 against milk-fat globule membrane (MAM-6). These cells were sometimes covered by cylindrical cells positive for foveolar-type mucin of the stomach (M1), and basal marginal cells of these nests expressed high molecular weight cytokeratins (34BE12). This study documents a new type of metaplasia of the gastric mucosa.
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Kushima, R., Borchard, F., von Hinüber, G. et al. Sebaceous gland metaplasia in cardiac-type mucosa of the oesophago-gastric junction. Vichows Archiv A Pathol Anat 428, 297–299 (1996). https://doi.org/10.1007/BF00196704
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DOI: https://doi.org/10.1007/BF00196704