Skip to main content
Log in

Occurrence of moulds in modern living and working environments

  • Published:
European Journal of Epidemiology Aims and scope Submit manuscript

Abstract

The occurrence of saprophytic moulds in indoor environments and their potential hazards to human health are discussed. In addition to mesophilic species, xerophilic moulds appear to be common, often developing together with mites. Allergic and non-allergic symptoms are reported when patients are exposed to moulds in homes, schools and working places. Airconditioning systems are consistently involved with mould development. Complaints of eye-, nose- and throat-irritation as well as fatigue seem to be correlated with unpleasant odours produced by abundant mould growth, but the relationship between the symptoms and the odours is not understood. The role of air-borne mycotoxins is discussed.

Methods to detect moulds in indoor environments are described. Because no single method or cultivation medium is sufficient to detect all the various indoor moulds, a combination of air sampling, direct microscopic examination and cultivation on both standard and low water activity media is recommended.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Al-DooryY. and DobsonJ.F. (1984): Mould Allergy. Lea & Febiger, Philadelphia.

    Google Scholar 

  2. Alexandrowicz J. and Smylx B. (1979): Mycotoxins and their role in oncogenesis with special reference to blood disease. - Polish med. Sci. Hist. Bull. pp. 25–30.

  3. AlexandrowiczJ., Adamek T., Laskownicka Z., Porebska A., Zemburowa K. (1973): Studies of precipitating antibodies for Aspergillus flavus antigens in patients with proliferative diseases. - Matena medica Polon. Nov. 4 (17).

  4. Austwick P.K.C. (1982): Humidifier fever - a mycologist's nightmare. In (Baxter M. ed.) Proc. Congr. Int. Soc. Human Animal Mycol.

  5. BernsteinR.S., SoresenW.G., GarabrantD., ReauxC., TreitmanR.D. (1983): Exposures to respirable, airborne Penicillium from a contaminated ventilation system: clinical, environmetal and epidemiological aspects. - J. American industrial Hyg. Assoc. 44: 161–169.

    Google Scholar 

  6. Bronswijk TE.M.H. van (1981): House dust biology for allergologists, acarologists and mycologists. -NIB Publ. Zeist.

  7. CampbellJ.A., KrydaM.J., TreuhaftM.W., MarxJ.J., RobertsR.C. (1983): Cheese workers' hypersensitivity pneumonitis. - Amer. Rev. Respir. Dis. 127: 495–496.

    Google Scholar 

  8. FranklandA.W. and FlayM.J. (1951): Dry rot as a cause of allergenic complaints. - Acta Allergol. 4: 186–200.

    Google Scholar 

  9. CariM., LavaudF. and PinonJ.M. (1983): Asthma à Penicillium candidum avec présence de précipitines chez un ouvrier fromages. - Bull. Soc. Fr. Mycol. Méd. 12: 135–137.

    Google Scholar 

  10. GellP.G.H., CoombsR.A. & LachmannP. (eds.) (1974): Clinical aspects of Immunology. 3rd edition section. Blackell Oxford.

    Google Scholar 

  11. GravesenS. (1984): The sedimentation method. In Jensen K.W. & Gravesen S.: Atlas of moulds in Europe causing respiratory allergy. ASK Publ. Copenhagen p. 59.

    Google Scholar 

  12. GravesenS. and JepsenJ.R. (1981): Luftfugtersyve. Et problem i den grafiske industri. - Ugeskrift for Laeger 14.3: 1211–1212.

    Google Scholar 

  13. Gravesen S., Larsen L. and Skov P. (1984): Aerobiology of schools and public institutions. Part of a study. Ecology Disease, in press.

  14. HanschirikE. (1983): Schimmelbildung in Wohnungen. -Bau und Bodenkrresp BBK 3: 3–6.

    Google Scholar 

  15. HartogB.J. (1984): The detection and quantification of fungi in food. In Samson R.A., Hoekstra E.S. and van Oorschot C.A.N. (eds.). Introduction to Food-borne fungi. Centraalbureau voor Schimmelcultures, Baarn, p. 206–211.

    Google Scholar 

  16. HintikkaE.L. (1978): Human stachybotryotoxicosis. In Willie T.D. and Morehouse L.G. (eds.). Mycotoxic fungi, mycotoxins, mycotoxicosis. An encyclopedic handbook. Vol. 3. Mycotoxicoses of man and plants: mycotoxin control and regulatory practices. Marcel Deker, New York, pp. 87–89.

    Google Scholar 

  17. HockingA.D. and PittJ.I. (1980): Dichloran-glycerol medium for enumeration of xerophilic fungi from low-moisture foods. - Appl. Environ. Microbiol. 39: 488–492.

    Google Scholar 

  18. Hyppel A. (1984): Finger print of a mould odor. In Indoor air: sensory and hyperreactivity reactions to sick buildings. Part 3. Proc. Third Conf. Indoor air quality and climate. Stockholm. pp. 443–447.

  19. JensenK.W. and GravesenS. (eds.) (1984): Atlas of moulds in Europe causing respiratory allergy. ASK Publ. Copenhagen.

    Google Scholar 

  20. KamienskiE., StawckiS. and WasowiezE. (1974): Volatile flavor compounds produced by molds of Aspergillus Penicillium and Fungi Imperfecti. -Appl. Microbiol. 27: 1001–1004.

    Google Scholar 

  21. KamphausenP.A. (1982): Schimmelpilze durch moderne Lueftungsprobleme? - Baugewerbe 62: 34–42.

    Google Scholar 

  22. KauppinenK., KuulialaO., BlorkstenF. (1983): Allergenic properties of a feed protein of microfungal origin. - Clinical Allergy 13: 69–73.

    Google Scholar 

  23. KikuchiT., MimuraT., HarmayaK., YanoH., ArimotoT., MasadaY. and InoueT. (1974): Volatile metabolite of aquatic fungi. Identification of 6-pentyl-α-pvrone from Trichoderma and Aspergillus species. - Chem. Pharm. Bull. 22: 1946–1948.

    Google Scholar 

  24. KikuchiT., KadotaS., SueharaH., NishiA. and TsubakiK. (1981): Odorous metabolites of a fungus, Chaetomium globosum Kunze ex Fr. Identification of Geosmin, a mustysmelling compound. -Chem. Pharm. Bull. 29: 1782–1784.

    Google Scholar 

  25. KikuchiT., KadotaS., SueharaH., NishiA., TsubakiK., YanoH. and HarimavaK. (1983): Odourous metabolites of Fungi, Chaetomium globosum Kunze e Fr. and Botrytis cinerea Pers. ex Fr., and a blue-green alga, Phormidium tenue (Meneghini) Gomont. - Chem. Pharm. Bull. 31: 659–663.

    Google Scholar 

  26. KingA.D. and PittJ.I. (1979): Dichloran-rose-bengal medium for enumeration and isolation of moulds from foods. - Appl. Environ. Microbiol. 37: 959–964.

    Google Scholar 

  27. KozakP.P., GallupJ., CumminsL.H. and GillmanS.A. (1980): Currently available methods for home mold surveys. I. Descriptions of techniques. - Annals of Allergy 45: 85–89.

    Google Scholar 

  28. KurupV.P., BarboriakJ.J. and FinkJ.N. (1984): Hypersensitivity pneumonitis. In Al-Doory Y. and Domson J.F. (eds.) Mould Allergy. Lea & Febiger, Philadelphia, pp. 216–243.

    Google Scholar 

  29. LeupenM.J. (1982): Vocht in huis- problemen rond en in h.et binnenmilieu. - Natur en Techniek 50: 616–631.

    Google Scholar 

  30. LeupenM.J. and VarekampH. (1966): Some constructional and physical considerations concerning the micro-climatological conditions affecting growth of the house-dust mite (Dermatophatogoides). - Proc. 5th Interasthma Congress. Pressa Trajectina, Utrecht, p. 244.

    Google Scholar 

  31. LustgraafB. v.d. (1977): Xerophilic fungi in mattress dust. - Mykosen 20: 101–106.

    Google Scholar 

  32. LustgraafB. v.d. (1978): Ecological relationships between xerophilic fungi and house-dust mites (Acarida: Pyroglyphidae). - Oecologia 33: 351–359.

    Google Scholar 

  33. LustgraafB. v.d. and Bronswijk J.E.H.M. van (1977): Fungi living in house dust. - Ann. Allergy 39: 152.

    Google Scholar 

  34. LustgraafB. v.d. and JordeW. (1977): Pyroglyphid mites, xerophilic fungi and allergenic activity in dust from hospital mattresses. - Acta Allergol. 32: 406.

    Google Scholar 

  35. NorthrupS.C. and KilburnK.H. (1978): The role of mycotoxins:n human pulmonary disease. In Willie T.D. and Morehouse L.G. (eds.) Mycotoxic fungi, mycotoxins, mvcotoxicosis. An encyclopedic handbook. Vol. 3. Mycotoxicoses of man and plants: mycotoxin control and regulatory practices. Marcel Dekker, New York, pp. 91–108.

    Google Scholar 

  36. O'Brien I.M., Bull J., Creamer B., Sepulveda R., Harries M., Burge P.S. and Pepys J. (19978): Asthma and extrinsic allergic alveolitis due to Merulius lacrymans. - Clinical Allergy 8: 535–542.

  37. PickeringC.A.C., MooreW.K.S., LaceyI., Holford-StrevensV.C. and PepysJ. (1976): Investigation of a respiratory disease with an airconditioning system. - Clinical Allergy 6: 109–118.

    Google Scholar 

  38. PittJ.I. (1975): Xerophilic fungi and the spoilage of foods of plant origin. In Duckworth R.B. (ed.). Water Relations of Foods. New York, Academic Press.

    Google Scholar 

  39. RijckaertG. (1981): Fast releasing allergens from some organisms living in house dust. - Ph. D. thesis, Univ. Nijmegen, Netherlands.

    Google Scholar 

  40. SaitoM., YamanishiT. and TsurutaO. (1979): Studies on the odor substances of Fungi. Part. 1. Identification of fungal odors produced on synthetic medium. - Rept. Natl. Food Res. Ind. 34: 67–69.

    Google Scholar 

  41. SamsonR.A., HoekstraE.S. and vanOorschotC.A.N. (1984): Introduction to Food-borne fungi. Centraalbureau voor Schimmelcultures, Baarn.

    Google Scholar 

  42. SnellerM.R. (1984): Mould allergy and climate condition. In Al-Doory Y. and Domson J.F. (eds.). Mould Allergy. Lea and Febiger, Philadelphia pp. 224–266.

    Google Scholar 

  43. SolomonW. (1984): Sampling techniques for airborne fungi. In: Mould allergy (Y. Al-Doory and J.F. Domson eds.), Lea & Febiger, Philadelphia, pp. 41–65.

    Google Scholar 

  44. Spieksma F.T.M. (1967): The house dust mite Dermatophagoides pteronyssinus, producer of the house dust allergens. Thesis Leiden.

  45. StaibF., FolkensU., TompakB., AbelT. and ThiefD. (1978a): A comparative study of antigens of Aspergillus fumigatus isolates from patients and soil of ornamental plants in the immuno diffusion test. - Zentbl. Bakt. Hyg. Abt. I, 242: 93.

    Google Scholar 

  46. StaibF., TompakB., ThielD. and AbelT. (1978b): Aspergillus fumigates in der Topferde von Zimmerpflanzen.- Bundesgesundheitsblatt 21: 209.

    Google Scholar 

  47. StaibF., TompakB., ThielD. and BlisseA. (1978c): Aspergillus fumigatus and Aspergillus niger in two potted ornamental plants, cactus (Epiphyllum truncatum) and Clivia miniata. Biological and epidemiological aspects. - Mycopathologia 66: 27.

    Google Scholar 

  48. StaibF. and RayendranC. (1980): Untersuchungen von Hydrokultur-Zimmerpflanzen auf menschenpathogene Aspergillus-Arten. - Hygiene und Medizin 5: 575–577.

    Google Scholar 

  49. StotzkyG. and SchenckS. (1974): Volatile organic compounds and microorganisms. In CRC Critical Reviews in Microbiology. - Baton Rouge USA, pp. 333–382.

    Google Scholar 

  50. ThörnqvistT. and LundströmH. (1982): Health hazards caused by fungi in stored wood chips. -Forest Products Journal 32: 29–32.

    Google Scholar 

  51. Urguhardt D.C.M. (1982): Condensation et development de moissures dans les maisons. - Batiment Int., pp. 88–99.

  52. VoorhorstR., SpieksmaF.T.M. and VarekampH. (1969): House dust atopy and house dust mite Dermatophagoides pteronyssinus (Trouessart 1897). Stafleu's Scient. Publ. Co., Leiden.

    Google Scholar 

  53. WrayB.B. and OsteenK.G. (7975): Mycotoxinproducing fungi from house associated with leukemia.- Arch. Environ. Health 30: 571–573.

    Google Scholar 

  54. YamamotoK. (1961): Studies on the metabolic products of Oospora sp. Part. I. Isolation and purification of two new compounds and eburicoic acid. - Agric. Biol. Chem. 25: 400–404.

    Google Scholar 

  55. YamamotoK. Nitta and YamamotoY. (1962): Studies on the metabolic products of Oospora sp. (Oospora astrigens). Part III. Chemical structure of oosponol (0–2). - Agric. Biol. Chem. 26: 486–493.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Samson, R.A. Occurrence of moulds in modern living and working environments. Eur J Epidemiol 1, 54–61 (1985). https://doi.org/10.1007/BF00162313

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00162313

Key words

Navigation