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Microvascular Dysfunction in the Context of Diabetic Neuropathy

  • Microvascular Complications—Neuropathy (D Ziegler, Section Editor)
  • Published:
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Abstract

Microvascular dysfunction in diabetes plays a crucial role in the development of diabetic complications. The skin, as one of the most accessible organs, serves as a model for the investigation of microvascular dysfunction. Several non-invasive, mostly laser-Doppler-based methods have been developed lately to assess microvascular function in the skin. Microvascular functional changes occur even in the prediabetic state and become more complex with overt diabetes, being exacerbated by the presence of peripheral and/or autonomic diabetic neuropathy. The present article aims at shedding light on the implication of endothelial and neurovascular dysfunction in microvascular changes in diabetes, highlighting the contribution of different forms of diabetic neuropathy.

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Alin Stirban declares that he has no conflict of interest.

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  1. Profil Institute for Metabolic Research, Hellersbergstr. 9, 41460, Neuss, Germany

    Alin Stirban

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This article is part of the Topical Collection on Microvascular Complications—Neuropathy

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Stirban, A. Microvascular Dysfunction in the Context of Diabetic Neuropathy. Curr Diab Rep 14, 541 (2014). https://doi.org/10.1007/s11892-014-0541-x

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