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A Review Molecular Typing Methods for Aspergillus flavus Isolates

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Abstract

Aspergillus flavus is the second most important Aspergillus species causing human infections. The importance of this fungus increases in regions with a dry and hot climate. Small phylogenetic studies in Aspergillus flavus indicate that the morphological species contains several genetically isolated species. Different genotyping methods have been developed and employed in order to better understand the genetic and epidemiological relationships between environmental and clinical isolates. Understanding pathogen distribution and relatedness is essential for determining the epidemiology of nosocomial infections and aiding in the design of rational pathogen control methods. Typing techniques can also give us a deeper understanding of the colonization pattern in patients. Most of these studies focused on Aspergillus fumigatus because it is medically the most isolated species. To date, there has not been any publication exclusively reviewing the molecular typing techniques for Aspergillus flavus in the literature. This article reviews all these different available methods for this organism.

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Authors and Affiliations

  1. Faculté de médecine, Laboratoire de biologie moléculaire parasitaire et fongique, 3029, Sfax, Tunisie

    Inès Hadrich, Fattouma Makni, Sourour Neji, Fatma Cheikhrouhou, Hayet Sellami & Ali Ayadi

  2. Fungal and parasitic molecular biology laboratory, School of Medicine Sfax, Sfax, Tunisia

    Ali Ayadi

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  1. Inès Hadrich
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  2. Fattouma Makni
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  3. Sourour Neji
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  5. Hayet Sellami
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  6. Ali Ayadi
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Correspondence to Inès Hadrich or Ali Ayadi.

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Hadrich, I., Makni, F., Neji, S. et al. A Review Molecular Typing Methods for Aspergillus flavus Isolates. Mycopathologia 172, 83–93 (2011). https://doi.org/10.1007/s11046-011-9406-x

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  • DOI: https://doi.org/10.1007/s11046-011-9406-x

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