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Brugnanin, a new syn-2,3-dihydrobenzofuran neolignan dioate from the mangrove Bruguiera gymnorrhiza

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Abstract

Brugnanin (1), a neolignan dioate, was isolated from a mangrove plant Bruguiera gymnorrhiza. Based on spectroscopic interpretation of MS, IR, and NMR data, 1 was elucidated as (7R*,8S*,E)-3-hydroxy-5,5′-dimethoxy-7-O-4′,8-3′-neolignan-7′-ene-9,9′-dioic acid dioctadecyl ester. MTT assay showed that 1 had weak inhibitory activity against growth of CNE-1 nasopharyngeal carcinoma cell line.

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ACKNOWLEDGMENT

This work was funded by the Ministry of Education of the People's Republic of China (“Chun Hui” Program 2003) and by the Guangxi Autonomous Region Department of Science and Technology (0342003-4).

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Authors and Affiliations

  1. Guangxi Cancer Institute Section of Laboratory Research, Nanning, 530021, China

    Suisheng Shang

  2. Department of Chemistry, Guangxi Medical University, Nanning, 530021, China

    Shengjing Long

Authors
  1. Suisheng Shang
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  2. Shengjing Long
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Correspondence to Suisheng Shang.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 2, pp. 147–149, March–April, 2008.

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Shang, S., Long, S. Brugnanin, a new syn-2,3-dihydrobenzofuran neolignan dioate from the mangrove Bruguiera gymnorrhiza . Chem Nat Compd 44, 186–189 (2008). https://doi.org/10.1007/s10600-008-9010-6

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  • DOI: https://doi.org/10.1007/s10600-008-9010-6

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