Abstract
Two carbapenem-resistant Klebsiella pneumoniae isolates producing the plasmid-encoded carbapenem-hydrolyzing OXA-48 were identified. These isolates, recovered from two patients hospitalized in two different hospitals in Tunisia in December 2010, were not clonally related. Molecular investigations showed that both isolates co-produced the narrow-spectrum β-lactamases TEM-1 and SHV-1, together with the extended-spectrum β-lactamase CTX-—15.
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Funding
This work was partially funded by a grant from the INSERM U914, the Ministère de l’Education Nationale et de la Recherche (UPRES-EA3539), Université Paris XI, France, by grants from the European Community (TROCAR, HEALTH-F3-2008-223031 and TEMPOtest-QC, HEALTH-2009-241742), and a grant from the Ministry of Scientific Research Technology and Competence Development (MSRTCD) of Tunisia.
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Lahlaoui, H., Poirel, L., Barguellil, F. et al. Carbapenem-hydrolyzing class D β-lactamase OXA-48 in Klebsiella pneumoniae isolates from Tunisia. Eur J Clin Microbiol Infect Dis 31, 937–939 (2012). https://doi.org/10.1007/s10096-011-1389-5
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DOI: https://doi.org/10.1007/s10096-011-1389-5