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Efficacy of different surgical techniques for peri-implant tissue preservation in immediate implant placement: a systematic review and meta-analysis

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Abstract

Introduction

Preserving peri-implant tissues after immediate implant placement (IIP), especially in aesthetic zones, is a topic of interest.

Objectives

This systematic review investigated the effects of currently available surgical procedures for preserving peri-implant tissue or ensuring dimensional stability following immediate implant placement.

Materials and methods

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement’s guidelines were followed, and articles were sought on the PubMed and Cochrane databases with no date restrictions. Only randomised clinical trials that evaluated changes in soft and hard tissues around immediately placed implants were included. Statistical analyses were performed, and the studies´ quality was assessed using the Cochrane Collaboration tool. The agreement between reviewers was assessed based on Cohen’s kappa statistics.

Results

Of the 14 studies that met the inclusion criteria, 11 were analysed in the meta-analysis (kappa = 0.814; almost perfect agreement). The use of connective tissue grafts resulted in a significantly greater improvement of the facial gingival level (MD = −0.51; 95% CI: −0.76 to −0.31; p = < .001), and the placement of bone grafts significantly reduced the horizontal resorption of the buccal bone (MD = −0.59; 95% CI: −0.78 to −0.39; p < .001).

Conclusion

Connective tissue grafts and bone grafts positively influence tissue preservation around immediately placed implants. Neither the flapless technique nor palatal implant positioning resulted in significant improvements to any of the investigated parameters. Additional longitudinal studies are required.

Clinical relevance

This meta-analysis is useful for discerning the effects of soft tissue augmentation, bone grafting, the flapless technique, and palatal implant positioning on preserving peri-implant tissues after immediate implant placement.

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References

  1. Schulte WHG (1976) The Tübinger immediate implant. Die Quintessenz 27(6):17–23

    PubMed  Google Scholar 

  2. Hämmerle CHF, Chen ST, Wilson TG (2004) Consensus statements and recommended clinical procedures regarding the placement of implants in extraction sockets. Int J Oral Maxillofac Implants 19(Suppl):26–28

    PubMed  Google Scholar 

  3. Lang NP, Pun L, Lau KY, Li KY, Wong MC (2012) A systematic review on survival and success rates of implants placed immediately into fresh extraction sockets after at least 1 year. Clin Oral Implants Res 23(Suppl 5):39–66

    Article  PubMed  Google Scholar 

  4. Slagter KW, den Hartog L, Bakker NA, Vissink A, Meijer HJ, Raghoebar GM (2014) Immediate placement of dental implants in the esthetic zone: a systematic review and pooled analysis. J Periodontol 85(7):e241–e250

    Article  PubMed  Google Scholar 

  5. Benic GI, Wolleb K, Sancho-Puchades M, Hämmerle CH (2012) Systematic review of parameters and methods for the professional assessment of aesthetics in dental implant research. J Clin Periodontol 39(Suppl 12):160–192

    Article  PubMed  Google Scholar 

  6. Araújo MG, Lindhe J (2005) Dimensional ridge alterations following tooth extraction. An experimental study in the dog. J Clin Periodontol 32(2):212–218

    Article  PubMed  Google Scholar 

  7. Chen ST, Buser D (2009) Clinical and esthetic outcomes of implants placed in postextraction sites. Int J Oral Maxillofac Implants 24(Suppl(January)):186–217

    PubMed  Google Scholar 

  8. Grunder U, Gracis S, Capelli M (2005) Influence of the 3-D bone-to-implant relationship on esthetics. Int J Periodontics Restorative Dent 25(2):113–119

    PubMed  Google Scholar 

  9. Al-Sabbagh M, Kutkut A (2015) Immediate implant placement: surgical techniques for prevention and management of complications. Dent Clin N Am 59(1):73–95

    Article  PubMed  Google Scholar 

  10. Testori T, Weinstein T, Scutellà F, Wang HL, Zucchelli G (2018) Implant placement in the esthetic area: criteria for positioning single and multiple implants. Periodontol 77(1):176–196

    Article  Google Scholar 

  11. Lin G-H, Chan H-L, Wang H-L (2014) Effects of currently available surgical and restorative interventions on reducing midfacial mucosal recession of immediately placed single-tooth implants: a systematic review. J Periodontol 85(1):92–102

    Article  PubMed  Google Scholar 

  12. Botticelli D, Berglundh T, Lindhe J (2004) Hard-tissue alterations following immediate implant placement in extraction sites. J Clin Periodontol 31(10):820–828

    Article  PubMed  Google Scholar 

  13. Paolantonio M, Dolci M, Scarano A, D’Archivio D, Di Placido G, Tumini V et al (2001) immediate implantation in fresh extraction sockets. A controlled clinical and histological study in man. J Periodontol 72(11):1560–1571

    Article  PubMed  Google Scholar 

  14. Covani U, Cornelini R, Barone A (2003) Bucco-lingual bone remodeling around implants placed into immediate extraction sockets: a case series. J Periodontol 74(2):268–273

    Article  PubMed  Google Scholar 

  15. Tarnow DP, Chu SJ (2011) Human histologic verification of osseointegration of an immediate implant placed into a fresh extraction socket with excessive gap distance without primary flap closure, graft, or membrane: a case report. Int J Periodontics Restorative Dent 31(5):515–521

    PubMed  Google Scholar 

  16. Chen ST, Darby IB, Reynolds EC (2007) A prospective clinical study of non- submerged immediate implants: clinical outcomes and esthetic results. Clin Oral Implants Res 18(5):552–562

    Article  PubMed  Google Scholar 

  17. Araújo MG, Linder E, Lindhe J (2011) Bio-Oss® collagen in the buccal gap at immediate implants: a 6-month study in the dog. Clin Oral Implants Res 22(1):1–8

    Article  PubMed  Google Scholar 

  18. Cardaropoli D, Tamagnone L, Roffredo A, Gaveglio L (2015) Soft tissue contour changes at immediate postextraction single-tooth implants with immediate restoration: a 12-month prospective cohort study. Int J Periodontics Restor Dent 35(2):191–198

    Article  Google Scholar 

  19. Tarnow DP, Chu SJ, Salama MA, Stappert CF, Salama H, Garber DA, Sarnachiaro GO, Sarnachiaro E, Gotta SL, Saito H (2014) Flapless postextraction socket implant placement in the esthetic zone: part 1. The effect of bone grafting and/or provisional restoration on facial-palatal ridge dimensional change-a retrospective cohort study. Int J Periodontics Restorative Dent 34(3):323–331

    Article  PubMed  Google Scholar 

  20. Edel A (1995) The use of a connective tissue graft for closure over an immediate implant covered with occlusive membrane. Clin Oral Implants Res 6:60–65

    Article  PubMed  Google Scholar 

  21. Kan JY, Rungcharassaeng K, Lozada JL (2005) Bilaminar subepithelial connective tissue grafts for immediate implant placement and provisionalization in the esthetic zone. J Calif Dent Assoc 33(11):865–871

    PubMed  Google Scholar 

  22. Kan JYK, Rungcharassaeng MSK (2011) Facial gingival tissue stability following immediate placement and provisionalization of maxillary anterior single implants: a 2- to 8-year follow-up. J Prosthet Dent 106(5):342

    Article  Google Scholar 

  23. Chung S, Rungcharassaeng K, Kan JYK, Roe P, Lozada JL (2011) Immediate single tooth replacement with subepithelial connective tissue graft using platform switching implants: a case series. J Oral Implantol 37(5):559–569

    Article  PubMed  Google Scholar 

  24. Bianchi AE, Sanfilippo F (2004) Single-tooth replacement by immediate implant and connective tissue graft: a 1-9-year clinical evaluation. Clin Oral Implants Res 15(3):269–277

    Article  PubMed  Google Scholar 

  25. Grunder U (2011) Crestal ridge width changes when placing implants at the time of tooth extraction with and without soft tissue augmentation after a healing period of 6 months: report of 24 consecutive cases. Int J Periodontics Restorative Dent 31(1):9–17

    PubMed  Google Scholar 

  26. Covani U, Marconcini S, Galassini G, Cornelini R, Santini S, Barone A (2007) Connective tissue graft used as a biologic barrier to cover an immediate implant. J Periodontol 78(8):1644–1649

    Article  PubMed  Google Scholar 

  27. Lee YM, Kim DY, Kim JY, Kim SH, Koo KT, Kim TI, Seol YJ (2012) Peri-implant soft tissue level secondary to a connective tissue graft in conjunction with immediate implant placement: a 2-year follow-up report of 11 consecutive cases. Int J Periodontics Restorative Dent 32(2):213–222

    PubMed  Google Scholar 

  28. Kim JI, Choi BH, Li J, Xuan F, Jeong SM (2009) Blood vessels of the peri-implant mucosa: a comparison between flap and flapless procedures. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107(4):508–512

    Article  PubMed  Google Scholar 

  29. Blanco J, Nuñez V, Aracil L, Muñoz F, Ramos I (2008) Ridge alterations following immediate implant placement in the dog: flap versus flapless surgery. J Clin Periodontol 35(7):640–648

    Article  PubMed  Google Scholar 

  30. Fickl S, Zuhr O, Wachtel H, Bolz W, Huerzeler M (2008) Tissue alterations after tooth extraction with and without surgical trauma: a volumetric study in the beagle dog. J Clin Periodontol 35(4):356–363

    Article  PubMed  Google Scholar 

  31. Job S, Bhat V, Naidu EM (2008) In vivo evaluation of crestal bone heights following implant placement with‘flapless’ and ‘with-flap’ techniques in sites of immediately loaded implants. Indian J Dent Res 19:320–325

    Article  PubMed  Google Scholar 

  32. Novaes AB Jr, Suaid F, Queiroz AC, Muglia VA, Souza SL, Palioto DB, Taba M Jr, Grisi MF (2012) Buccal bone plate remodeling after immediate implant placement with and without synthetic bone grafting and flapless surgery: radiographic study in dogs. J Oral Implantol 38(6):687–698

    Article  PubMed  Google Scholar 

  33. Esposito M, Maghaireh H, Grusovin MG, Ziounas I, Worthington HV (2012) Soft tissue management for dental implants: what are the most effective techniques? A Cochrane systematic review. Eur J Oral Implantol 5(3):221–238

    PubMed  Google Scholar 

  34. Lin G-H, Chan H-L, Bashutski JD, Oh T-J, Wang H-L (2014) The effect of flapless surgery on implant survival and marginal bone level: a systematic review and meta-analysis. J Periodontol 85(5):e91–e103

    Article  PubMed  Google Scholar 

  35. Araújo MG, Sukekava F, Wennström JL, Lindhe J (2005) Ridge alterations following implant placement in fresh extraction sockets: an experimental study in the dog. J Clin Periodontol 32(6):645–652

    Article  PubMed  Google Scholar 

  36. Caneva M, Botticelli D, Salata LA, Souza SLS, Bressan E, Lang NP (2010) Flap vs. “flapless” surgical approach at immediate implants: a histomorphometric study in dogs. Clin Oral Implants Res 21(12):1314–1319

    Article  PubMed  Google Scholar 

  37. Becker W, Wikesjö UM, Sennerby L, Qahash M, Hujoel P, Goldstein M, Turkyilmaz I (2006) Histologic evaluation of implants following flapless and flapped surgery: a study in canines. J Periodontol 77(10):1717–1722

    Article  PubMed  Google Scholar 

  38. De Bruyn H, Atashkadeh M, Cosyn J, van de Velde T (2011) Clinical outcome and bone preservation of single TiUnite™ implants installed with flapless or flap surgery. Clin Implant Dent Relat Res 13(3):175–183

    Article  PubMed  Google Scholar 

  39. Caneva M, Salata LA, de Souza SS, Baffone G, Lang NP, Botticelli D (2010) Influence of implant positioning in extraction sockets on osseointegration: histomorphometric analyses in dogs. Clin Oral Implants Res 21:43–49

    Article  PubMed  Google Scholar 

  40. Favero G, Botticelli D, Favero G, García B, Mainetti T, Lang NP (2013) Alveolar bony crest preservation at implants installed immediately after tooth extraction: an experimental study in the dog. Clin Oral Implants Res 24(1):7–12

    Article  PubMed  Google Scholar 

  41. Tomasi C, Sanz M, Cecchinato D, Pjetursson B, Ferrus J, Lang NP, Lindhe J (2010) Bone dimensional variations at implants placed in fresh extraction sockets: a multilevel multivariate analysis. Clin Oral Implants Res 21(1):30–36

    Article  PubMed  Google Scholar 

  42. Evans CD, Chen ST (2008) Esthetic outcomes of immediate implant placements. Clin Oral Implants Res 19(1):73–80

    PubMed  Google Scholar 

  43. Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA (2015) PRISMA-P Group. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev 4(1):1

    Article  PubMed  PubMed Central  Google Scholar 

  44. Higgins, JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors) (2020) Cochrane handbook for systematic reviews of interventions version 6.1 (updated September 2020). Cochrane. 2453–2457 p

  45. Higgins JPT, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21(11):1539–1558

    Article  PubMed  Google Scholar 

  46. Bora P (2015) Effect of platelet rich fibrin (PRF) on peri-implant soft tissue and crestal bone in one-stage implant placement: a randomized controlled trial. J Clin Diagn Res 9(4):ZC18–ZC21

    Google Scholar 

  47. Cordaro L, Torsello F, Roccuzzo M (2009) Clinical outcome of submerged vs. non-submerged implants placed in fresh extraction sockets. Clin Oral Implants Res 20(12):1307–1313

    Article  PubMed  Google Scholar 

  48. De Angelis N, Felice P, Pellegrino G, Camurati A, Gambino P, Esposito M (2011) Guided bone regeneration with and without a bone substitute at single post-extractive implants: 1-year post-loading results from a pragmatic multicentre randomised controlled trial. Eur J Oral Implantol 4(4):313–325

    PubMed  Google Scholar 

  49. Zuffetti F, Esposito M, Capelli M, Galli F, Testori T, Del Fabbro M (2013) Socket grafting with or without buccal augmentation with an organic bovine bone at immediate post-extractive implants: 6-month after loading results from a multicenter randomised controlled clinical trial. Eur J Oral Implantol 6(3):239–250

    PubMed  Google Scholar 

  50. Bramanti E, Norcia A, Cicciù M, Matacena G, Cervino G, Troiano G, Zhurakivska K, Laino L (2018) Postextraction dental implant in the aesthetic zone, socket shield technique versus conventional protocol. J Craniofac Surg 29(4):1037–1041

    Article  PubMed  Google Scholar 

  51. Cardaropoli D, Gaveglio L, Gherlone E, Cardaropoli G (2014) Soft tissue contour changes at immediate implants: a randomized controlled clinical study. Int J Periodontics Restorative Dent 34(5):631–637

    Article  PubMed  Google Scholar 

  52. Mounir M, Beheiri G, Assessment WE (2014) Assessment of marginal bone loss using full thickness versus partial thickness flaps for alveolar ridge splitting and immediate implant placement in. Int J Oral Maxillofac Surg 43(11):1373–1380

    Article  PubMed  Google Scholar 

  53. Hazzaa HHA, El-Kilani NS, Elsayed SA, Abd El Massieh PM (2019) Evaluation of immediate implants augmented with autogenous bone/melatonin composite graft in the esthetic zone: a randomized controlled trial. J Prosthodont 28(2):e637–e642

    Article  PubMed  Google Scholar 

  54. Chen ST, Darby IB, Adams GG, Reynolds EC (2005) A prospective clinical study of bone augmentation techniques at immediate implants. Clin Oral Implants Res 16(2):176–184

    Article  PubMed  Google Scholar 

  55. Rungcharassaeng K, Kan JYK, Yoshino S, Morimoto T, Zimmerman G (2012) Immediate implant placement and provisionalization with and without a connective tissue graft: an analysis of facial gingival tissue thickness. Int J Periodontics Restorative Dent 32(6):657–663

    PubMed  Google Scholar 

  56. Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics. 33(1):159–174

    Article  PubMed  Google Scholar 

  57. Zuiderveld EG, Meijer HJA, den Hartog L, Vissink A, Raghoebar GM (2018) Effect of connective tissue grafting on peri-implant tissue in single immediate implant sites: a RCT. J Clin Periodontol 45(2):253–264

    Article  PubMed  Google Scholar 

  58. van Nimwegen WG, Raghoebar GM, Zuiderveld EG, Jung RE, Meijer HJA, Mühlemann S (2018) Immediate placement and provisionalization of implants in the aesthetic zone with or without a connective tissue graft: a 1-year randomized controlled trial and volumetric study. Clin Oral Implants Res 29(7):671–678

    Article  PubMed  PubMed Central  Google Scholar 

  59. Yoshino S, Kan JY, Rungcharassaeng K, Roe P, Lozada JL (2014) Effects of connective tissue grafting on the facial gingival level following single immediate implant placement and provisionalization in the esthetic zone: a 1-year randomized controlled prospective study. Int J Oral Maxillofac Implants 29(2):432–440

    Article  PubMed  Google Scholar 

  60. Migliorati M, Amorfini L, Signori A, Biavati AS, Benedicenti S (2015) Clinical and aesthetic outcome with post-extractive implants with or without soft tissue augmentation: a 2-year randomized clinical trial. Clin Implant Dent Relat Res 17(5):983–995

    Article  PubMed  Google Scholar 

  61. Frizzera F, de Freitas R, Muñoz-Chávez O, Cabral G, Shibli J, Marcantonio E (2018) Impact of soft tissue grafts to reduce Peri-implant alterations after immediate implant placement and provisionalization in compromised sockets.pdf. Int J Periodontics Restorative Dent 39(3):381–389

    Article  PubMed  Google Scholar 

  62. Paknejad M, Akbari S, Aslroosta H, Panjnoush M, Hajheidary S (2017) Effect of flapless immediate implantation and filling the buccal gap with xenograft material on the buccal bone level: a randomized clinical trial. J Dent (Tehran) 14(6):344–351

    Google Scholar 

  63. Sanz M, Lindhe J, Alcaraz J, Sanz-Sanchez I, Cecchinato D (2017) The effect of placing a bone replacement graft in the gap at immediately placed implants: a randomized clinical trial. Clin Oral Implants Res 28(8):902–910

    Article  PubMed  Google Scholar 

  64. Girlanda FF, Feng HS, Corrêa MG, Casati MZ, Pimentel SP, Ribeiro FV, Cirano FR (2019) Deproteinized bovine bone derived with collagen improves soft and bone tissue outcomes in flapless immediate implant approach and immediate provisionalization: a randomized clinical trial. Clin Oral Investig 23(10):3885–3893

    Article  PubMed  Google Scholar 

  65. Mastrangelo F, Gastaldi G, Vinci R, Troiano G, Tettamanti L, Gherlone E, Lo Muzio L (2018) Immediate postextractive implants with and without bone graft: 3-year follow-up results from a multicenter controlled randomized trial. Implant Dent 27(6):638–645

    Article  PubMed  Google Scholar 

  66. Grassi FR, Grassi R, Rapone B, Alemanno G, Balena A, Kalemaj Z (2019) Dimensional changes of buccal bone plate in immediate implants inserted through open flap, open flap and bone grafting and flapless techniques: a cone-beam computed tomography randomized controlled clinical trial. Clin Oral Implants Res 30(12):1155–1164

    Article  PubMed  Google Scholar 

  67. Stoupel J, Lee CT, Glick J, Sanz-Miralles E, Chiuzan C, Papapanou PN (2016) Immediate implant placement and provisionalization in the aesthetic zone using a flapless or a flap-involving approach: a randomized controlled trial. J Clin Periodontol 43(12):1171–1179

    Article  PubMed  Google Scholar 

  68. Esposito M, González-García A, Peñarrocha Diago M, Fernández Encinas R, Trullenque-Eriksson A, Xhanari E, Peñarrocha Oltra D (2018) Natural or palatal positioning of immediate post-extractive implants in the aesthetic zone? 1-year results of a multicentre randomised controlled trial. Eur J Oral Implantol 11(2):189–200

    PubMed  Google Scholar 

  69. Peñarrocha-Oltra D, Peñarrocha-Diago M, Encinas RF, Ippolito DR, Xhanari E, Esposito M (2019) Natural or palatal positioning of immediate post-extractive implants in the aesthetic zone? Three-year results of a multicentre randomised controlled trial. Int J Oral Implantol (Berl) 12(2):181–194

    Google Scholar 

  70. Belser UC, Grütter L, Vailati F, Bornstein MM, Weber H-P, Buser D (2009) Outcome evaluation of early placed maxillary anterior single-tooth implants using objective esthetic criteria: a cross-sectional, retrospective study in 45 patients with a 2- to 4-year follow-up using pink and white esthetic scores. J Periodontol 80(1):140–151

    Article  PubMed  Google Scholar 

  71. Fürhauser R, Florescu D, Benesch T, Haas R, Mailath G, Watzek G (2005) Evaluation of soft tissue around single-tooth implant crowns: the pink esthetic score. Clin Oral Implants Res 16(6):639–644

    Article  PubMed  Google Scholar 

  72. Lin CY, Chen Z, Pan WL, Wang HL (2018) Impact of timing on soft tissue augmentation during implant treatment: a systematic review and meta-analysis. Clin Oral Implants Res 29(5):508–521

    Article  PubMed  Google Scholar 

  73. Lee C-T, Tao C-Y, Stoupel J (2016) REV The effect of subepithelial connective tissue on esthetic outcomes after immediate implant placement: systematic review graft placement. J Periodontol 87(2):156–167

    Article  PubMed  Google Scholar 

  74. Tarnow DP, Magner AW, Fletcher P (1992) The effect of the distance from the contact point to the crest of bone on the presence or absence of the interproximal dental papilla. J Periodontol 63(12):995–996

    Article  PubMed  Google Scholar 

  75. Buser D, Martin W, Belser UC (2004) Optimizing esthetics for implant restorations in the anterior maxilla: anatomic and surgical considerations. Int J Oral Maxillofac Implants 19(Suppl):43–61

    PubMed  Google Scholar 

  76. Steigmann M, Monje A, Chan H-L, Wang H-L (2014) Emergence profile design based on implant position in the esthetic zone. Int J Periodontics Restorative Dent 34(4):559–563

    Article  PubMed  Google Scholar 

  77. Su H, Gonzalez-Martin O, Weisgold A, Lee E (2010) Considerations of implant abutment and crown contour: critical contour and subcritical contour. Int J Periodontics Restorative Dent 30(4):335–343

    PubMed  Google Scholar 

  78. Gómez-Meda R, Montoya-Salazar V, Dalmau S, Torres-Lagares D (2018) Three steps to maintain predictable interdental papilla and gingiva emergence profiles in immediate implant placement. A 3-year follow-up case report. J Clin Exp Dent 10(5):e513–e519

    PubMed  PubMed Central  Google Scholar 

  79. Thoma DS, Buranawat B, Hämmerle CHF, Held U, Jung RE (2014) Efficacy of soft tissue augmentation around dental implants and in partially edentulous areas: a systematic review. J Clin Periodontol 41:S77–S91

    Article  PubMed  Google Scholar 

  80. Thoma DS, Naenni N, Figuero E, Hämmerle CHF, Schwarz F, Jung RE, Sanz-Sánchez I (2018) Effects of soft tissue augmentation procedures on peri-implant health or disease: a systematic review and meta-analysis. Clin Oral Implants Res 29:32–49

    Article  PubMed  Google Scholar 

  81. Zuhr O, Baumer D, Hurzeler M (2014) The addition of soft tissue replacement grafts in plastic periodontal and implant surgery: critical elements in design and execution. J Clin Periodontol 41(Suppl 15):S123–S142

    Article  PubMed  Google Scholar 

  82. Tavelli L, Barootchi S, Greenwell H, Wang HL (2019) Is a soft tissue graft harvested from the maxillary tuberosity the approach of choice in an isolated site? J Periodontol 90(8):821–825

    Article  PubMed  Google Scholar 

  83. Dellavia C, Ricci G, Pettinari L, Allievi C, Grizzi F, Gagliano N (2014) Human palatal and tuberosity mucosa as donor sites for ridge augmentation. Int J Periodontics Restorative Dent 34(2):179–186

    Article  PubMed  Google Scholar 

  84. Schneider D, Grunder U, Ender A, Hämmerle CH, Jung RE (2011) Volume gain and stability of peri-implant tissue following bone and soft tissue augmentation: 1-year results from a prospective cohort study. Clin Oral Implants Res 22(1):28–37

    Article  PubMed  Google Scholar 

  85. Rojo E, Stroppa G, Sanz-Martin I, Gonzalez-Martín O, Alemany AS, Nart J (2018) Soft tissue volume gain around dental implants using autogenous subepithelial connective tissue grafts harvested from the lateral palate or tuberosity area. A randomized controlled clinical study. J Clin Periodontol 45(4):495–503

    Article  PubMed  Google Scholar 

  86. Linkevicius T, Puisys A, Linkeviciene L, Peciuliene V, Schlee M (2015) Crestal bone stability around implants with horizontally matching connection after soft tissue thickening: a prospective clinical trial. Clin Implant Dent Relat Res 17(3):497–508

    Article  PubMed  Google Scholar 

  87. Antunes AA, Oliveira Neto P, de Santis E, Caneva M, Botticelli D, Salata LA (2013) Comparisons between Bio-Oss® and Straumann® Bone Ceramic in immediate and staged implant placement in dogs mandible bone defects. Clin Oral Implants Res 24(2):135–142

    Article  PubMed  Google Scholar 

  88. Degidi M, Daprile G, Nardi D, Piattelli A (2013) Buccal bone plate in immediately placed and restored implant with Bio-Oss® collagen graft: a 1-year follow-up study. Clin Oral Implants Res 24(11):1201–1205

    PubMed  Google Scholar 

  89. Faria-Almeida R, Astramskaite-Januseviciene I, Puisys A, Correia F (2019) Extraction socket preservation with or without membranes, soft tissue influence on post extraction alveolar ridge preservation: a systematic review. J Oral Maxillofac Res 10(3):1–12

    Article  Google Scholar 

  90. de Carvalho Fomiga M, Dayube URC, Chiapetti CK, de Rossi FD, Shibli JA (2019) Socket preservation using a (dense) PTFE barrier with or without xenograft material: a randomized clinical trial. Materials (Basel) 12(18):2902

    Article  Google Scholar 

  91. Clementini M, Tiravia L, De Risi V, Vittorini Orgeas G, Mannocci A, De Sanctis M (2015) Dimensional changes after immediate implant placement with or without simultaneous regenerative procedures: a systematic review and meta-analysis. J Clin Periodontol 42(7):666–677

    Article  PubMed  Google Scholar 

  92. AlKudmani H, Jasser RAL, Andreana S (2017) REV SIST Is bone graft or guided bone regeneration needed when placing immediate dental implants? A systematic review. Implant Dent 26(6):936–944

    Article  PubMed  Google Scholar 

  93. Wilson TG, Schenk R, Buser D, Cochran D (1998) Implants placed in immediate extraction sites: a report of histologic and histometric analyses of human biopsies. Int J Oral Maxillofac Implants 13(3):333–341

    PubMed  Google Scholar 

  94. Naji BM, Abdelsameaa SS, Alqutaibi AY, Said Ahmed WM (2020) Immediate dental implant placement with a horizontal gap more than two millimetres: a randomized clinical trial. Int J Oral Maxillofac Surg

  95. Vignoletti F, Sanz M (2014) Immediate implants at fresh extraction sockets: from myth to reality. Periodontol 66(1):132–152

    Article  Google Scholar 

  96. Canullo L, Iurlaro G, Iannello G (2009) Double-blind randomized controlled trial study on post-extraction immediately restored implants using the switching platform concept: soft tissue response. Preliminary report. Clin Oral Implants Res 20(4):414–420

    Article  PubMed  Google Scholar 

  97. Raes F, Cosyn J, Crommelinck E, Coessens P, De Bruyn H (2011) Immediate and conventional single implant treatment in the anterior maxilla: 1-year results of a case series on hard and soft tissue response and aesthetics. J Clin Periodontol 38(4):385–394

    Article  PubMed  Google Scholar 

  98. Lee CT, Chiu TS, Chuang SK, Tarnow D, Stoupel J (2014) Alterations of the bone dimension following immediate implant placement into extraction socket: systematic review and meta-analysis. J Clin Periodontol 41(9):914–926

    Article  PubMed  Google Scholar 

  99. Khzam N, Arora H, Kim P, Fisher A, Mattheos N, Ivanovski S (2015) Systematic review of soft tissue alterations and esthetic outcomes following immediate implant placement and restoration of single implants in the anterior maxilla. J Periodontol 86(12):1321–1330

    Article  PubMed  Google Scholar 

  100. Ferrus J, Cecchinato D, Pjetursson EB, Lang NP, Sanz M, Lindhe J (2010) Factors influencing ridge alterations following immediate implant placement into extraction sockets. Clin Oral Implants Res 21(1):22–29

    Article  PubMed  Google Scholar 

  101. Bittner N, Schulze-Späte U, Silva C, Da Silva JD, Kim DM, Tarnow D, Gil MS, Ishikawa-Nagai S (2019) Changes of the alveolar ridge dimension and gingival recession associated with implant position and tissue phenotype with immediate implant placement: A randomised controlled clinical trial. Int J Oral Implantol (Berl) 12(4):469–480

    Google Scholar 

  102. Crespi R, Capparé P, Crespi G, Gastaldi G, Romanos G, Gherlone E (2018) Tissue remodeling in immediate versus delayed prosthetic restoration in fresh socket implants in the esthetic zone: four-year follow-up. Int J Periodontics Restorative Dent 38:s97–s103

    Article  PubMed  Google Scholar 

  103. De Rouck T, Collys K, Wyn I, Cosyn J (2009) Instant provisionalization of immediate single-tooth implants is essential to optimize esthetic treatment outcome. Clin Oral Implants Res 20(6):566–570

    PubMed  Google Scholar 

  104. Chan HL, George F, Wang IC, Suárez López Del Amo F, Kinney J, Wang HL (2019) A randomized controlled trial to compare aesthetic outcomes of immediately placed implants with and without immediate provisionalization. J Clin Periodontol 46(10):1061–1069

    Article  PubMed  Google Scholar 

  105. Slagter KW, Meijer HJA, Bakker NA, Vissink A, Raghoebar GM (2015) Feasibility of immediate placement of single-tooth implants in the aesthetic zone: a 1-year randomized controlled trial. J Clin Periodontol 42(8):773–782

    Article  PubMed  Google Scholar 

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Manuel-María Romero-Ruiz, José Luis Gutiérrez-Pérez, Maria Ángeles Serrera-Figallo: data curation, Sara Bakkali and Daniel Torres-Lagares; formal analysis, María Rizo-Gorrita; investigation, Sara Bakkali, María Rizo-Gorrita, Daniel Torres-Lagares, and Maria Ángeles Serrera-Figallo; methodology, Sara Bakkali, Manuel-María Romero-Ruiz, José Luis Gutiérrez-Pérez, Daniel Torres-Lagares, and Maria Ángeles Serrera-Figallo; project administration, Maria Ángeles Serrera-Figallo; software, Maria Ángeles Serrera-Figallo; supervision, Manuel-María Romero-Ruiz, José Luis Gutiérrez-Pérez, and Daniel Torres-Lagares; validation, Manuel-María Romero-Ruiz, José Luis Gutiérrez-Pérez, Daniel Torres-Lagares, and Maria Ángeles Serrera-Figallo; visualisation, Sara Bakkali and María Rizo-Gorrita; writing (original draft), Sara Bakkali, María Rizo-Gorrita, Manuel-María Romero-Ruiz, José Luis Gutiérrez-Pérez, Daniel Torres-Lagares, and Maria Ángeles Serrera-Figallo; writing (reviewing and editing), Sara Bakkali, María Rizo-Gorrita, Manuel-María Romero-Ruiz, José Luis Gutiérrez-Pérez, Daniel Torres-Lagares, and Maria Ángeles Serrera-Figallo.

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Correspondence to José Luis Gutiérrez-Pérez or Daniel Torres-Lagares.

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Bakkali, S., Rizo-Gorrita, M., Romero-Ruiz, MM. et al. Efficacy of different surgical techniques for peri-implant tissue preservation in immediate implant placement: a systematic review and meta-analysis. Clin Oral Invest 25, 1655–1675 (2021). https://doi.org/10.1007/s00784-021-03794-y

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