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Identification of a gammaherpesvirus belonging to the malignant catarrhal fever group of viruses in Pyrenean chamois (Rupicapra p. pyrenaica)

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Abstract

High prevalence (46 %) of a gammaherpesvirus was confirmed by molecular detection in the lungs of hunted Pyrenean chamois. The partial glycoprotein B sequence up to the DNA polymerase gene showed 96.6 % nucleotide sequence identity to the Rupicapra rupicapra gammaherpesvirus 1 and 81.5 % to ovine herpesvirus 2. This novel sequence clusters within sequences derived from the malignant catarrhal fever group of viruses, and the corresponding virus is tentatively named Rupicapra pyrenaica gammaherpesvirus 1 (RpHV-1). No specific histological lesions were associated with RpHV-1, nor were any detrimental effects on host health. The epidemiological, phylogenetic and histopathological results suggest that Pyrenean chamois is the natural host of RpHV-1.

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Acknowledgments

The authors are grateful to the rangers of the NGRFS and to its Director Jordi Xifra for their support and fieldwork assistance, and to Elena Neves and Verónica Nogal for their technical assistance at INIA-CISA.

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Authors and Affiliations

  1. Servei d’Ecopatologia de Fauna Salvatge, Departament de Medicina i Cirurgia Animals, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain

    Xavier Fernández-Aguilar, Oscar Cabezón, Roser Velarde, Gregorio Mentaberre, Emmanuel Serrano, Santiago Lavín & Jorge Ramón López-Olvera

  2. IRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain

    Xavier Fernández-Aguilar & Oscar Cabezón

  3. Centro de Investigación en Sanidad Animal (INIA-CISA), Carretera Algete a El Casar s/n, 28140, Valdeolmos, Madrid, Spain

    Fernando Esperón, Verónica Delicado & María Jesús Muñoz

  4. CESAM, Departamento de Biologia Universidade de Aveiro, Aveiro, Portugal

    Emmanuel Serrano

Authors
  1. Xavier Fernández-Aguilar
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  2. Fernando Esperón
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  3. Oscar Cabezón
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  4. Roser Velarde
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  7. María Jesús Muñoz
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  8. Emmanuel Serrano
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  9. Santiago Lavín
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  10. Jorge Ramón López-Olvera
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Corresponding author

Correspondence to Xavier Fernández-Aguilar.

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Funding

This study was funded by the Spanish MICINN (grant number CGL2009-11631). X. Fernández-Aguilar received a predoctoral grant (FI-DGR 2013) from the Generalitat de Catalunya, and E. Serrano was supported by the postdoctoral program (SFRH/BPD/96637/2013) of the Fundação para a Ciência e a Tecnologia, Portugal.

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The authors declare that they have no conflict of interest.

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This article does not contain any studies with live animals performed by any of the authors.

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Fernández-Aguilar, X., Esperón, F., Cabezón, O. et al. Identification of a gammaherpesvirus belonging to the malignant catarrhal fever group of viruses in Pyrenean chamois (Rupicapra p. pyrenaica). Arch Virol 161, 3249–3253 (2016). https://doi.org/10.1007/s00705-016-3011-8

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  • DOI: https://doi.org/10.1007/s00705-016-3011-8

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