Skip to main content

Advertisement

Log in

Ovarian metastases caused by cholangiocarcinoma: a rare Krükenberg's tumour simulating a primary neoplasm of the ovary: a two-case study

  • Case Report
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Introduction

Ovarian metastases represent 10% of all ovarian malignancies. They are characterized by their ability to occasionally reproduce mimicking the clinical and morphological appearance of primary tumours, making diagnosis difficult. Most of these tumours originate in the digestive tract, the best known being Krukenberg's tumour in the stomach. Cholangiocarcinomas are rare neoplasias that very rarely affect the ovary. Their retroperitoneal location and low histological specificity in the ovary may lead to a misdiagnosis. This makes it necessary to accurately assess all clinical, radiological and morphological symptoms so as to avoid inappropriate treatments in affected patients.

Case report

Two cases of biliary cholangiocarcinomas simulating an ovarian neoplasia are reported.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1A–C.
Fig. 2.
Fig. 3.
Fig. 4.

Similar content being viewed by others

References

  1. Anthony PP (1973) Primary carcinoma of the liver. J Pathol 110:37–48

    CAS  PubMed  Google Scholar 

  2. Boring CC, Squires TS, Tong T (1993) Cancer statistics, 1993. CA Cancer J Clin 43:7–26

    PubMed  Google Scholar 

  3. Boring CC, Squires TS, Tong T, Montgomery S (1993) Cancer statistics 1994. CA Cancer J Clin 44:7–26

    Google Scholar 

  4. Chen MF (1999) Peripheral cholangiocarcinoma (cholangiocellular carcinoma): clinical features, diagnosis and treatment. J Gastroenterol Hepatol 14:1144–1149

    Article  CAS  PubMed  Google Scholar 

  5. Kim KH, Kim CD, Lee HS, Hyun JH, Kim YS, Iim IS (1999) Bilateral ovarian carcinoma metastatic from the ampulla of Vater: a rare Krukenberg tumor. J Korean Med Sci 14:220–222

    CAS  PubMed  Google Scholar 

  6. Las RH, Hart WR (1987) Intestinal adenocarcinomas metastatic to the ovaries. A clinicopathologic evaluation of 22 cases. Am J Surg Pathol 11:114–121

    PubMed  Google Scholar 

  7. Lashgari M, Behmaram B, Hoffman JS, Garcia J (1992) Primary biliary carcinoma with metastasis to the ovary. Gynecol Oncol 47:272–274

    CAS  PubMed  Google Scholar 

  8. Loke TK, Lo SS, Chan CS (1997) Case report: Krukenberg's tumours arising from a primary duodenojejunal adenocarcinoma. Clin Radiol 52:154–155

    CAS  PubMed  Google Scholar 

  9. Piver MS (2000) Ovarian epithelial cancer. In: Piver MSA (ed) Handbook of gynecologic oncology. Marban, Madrid

  10. Tjalma WA, Schatteman E, Goovaerts G, Verkinderen L, Van-den Borre F, Keersmaekers G (2000) Adenocarcinoid of the appendix presenting as disseminated ovarian carcinoma: report of a case. Surg Today 30:78–81

    CAS  PubMed  Google Scholar 

  11. Unterweger M, Caduff R, Bajka M, Kotz Kubi-Hucu R (1999) Krukenberg syndrome in metastatic gallbladder adenocarcinoma. Schweiz Rundsch Med Prax 88:1320–1323

    CAS  PubMed  Google Scholar 

  12. Wheelock MC, Frable WJ, Urnes PD (1962) Bizarre metastasis from malignant neoplasms. Am J Clin Pathol 37:45–49

    Google Scholar 

  13. Young RH, Hart WR (1989) Metastases from carcinomas of the pancreas simulating primary mucinous tumors of the ovary: a report of seven cases. Am J Surg Pathol 13:748–756

    CAS  PubMed  Google Scholar 

  14. Young RH, Scully RE (1987) Metastatic tumors of the ovary. In: Kurman RJ (ed) Blaustein's pathology of the female genital tract. Springer, New York Berlin Heidelberg, pp 742–768

  15. Young RH, Scully RE (1989) Ovarian metastases from carcinoma of the pancreas simulating primary mucinous tumor of the ovary: a report of seven cases. Int J Surg Pathol 13:748–756

    CAS  Google Scholar 

  16. Young RH, Scully RE (1990) Ovarian metastases from carcinoma of the gallbladder and extrahepatic biliary ducts simulating primary tumors of the ovary: a report of six cases. Int J Gynecol Pathol 9:60–72

    Google Scholar 

  17. Young RH, Scully RE (1991) Metastatic tumors in the ovary: a problem-oriented approach and review of the recent literature. Semin Diagn Pathol 8:250–276

    CAS  PubMed  Google Scholar 

  18. Young RH, Scully RE (2001) Differential diagnosis of ovarian tumors based primarily on their patterns and cell types. Semin Diagn Pathol 18:161–235

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. García.

Rights and permissions

Reprints and permissions

About this article

Cite this article

García, A., De la Torre, J., Castellví, J. et al. Ovarian metastases caused by cholangiocarcinoma: a rare Krükenberg's tumour simulating a primary neoplasm of the ovary: a two-case study. Arch Gynecol Obstet 270, 281–284 (2004). https://doi.org/10.1007/s00404-003-0508-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00404-003-0508-7

Keywords

Navigation