Abstract.
Pyruvic acid is an important organic acid widely used in the chemical and drug, as well as agrochemical, industries. Compared with the chemical method, biotechnological production of pyruvic acid is an alternative approach because of the low cost. An overview of biotechnological production of pyruvate, including direct fermentative production employing eukaryotic and prokaryotic microorganisms, production by a resting cell method and an enzymatic method as well as the recovery of pyruvate, is discussed. A multi-vitamin auxotrophic yeast strain, Torulopsis glabrata, has been used in the commercial production of pyruvate; emphasis is therefore placed on the mechanism and characteristics of pyruvate production by this strain.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received revision: 30 July 2001
Electronic Publication
Rights and permissions
About this article
Cite this article
Li, .Y., Chen, .J. & Lun, .SY. Biotechnological production of pyruvic acid. Appl Microbiol Biotechnol 57, 451–459 (2001). https://doi.org/10.1007/s002530100804
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s002530100804