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The relationship between varicocele and semen nitric oxide concentrations

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Abstract

We investigated the relationship between seminal plasma nitric oxide (NO) concentrations and conventional semen parameters in patients with varicocele. Semen samples were obtained from infertile patients with varicocele (n=55) and from normal controls (n=48). The mean NO concentration in the seminal plasma of patients with varicocele was significantly higher than that of the controls (P < 0.01). A significant negative correlation was noted between NO and sperm motility (r=−0.29, P=0.003), NO and sperm concentration (r=−0.26, P=0.008) and NO and normal morphology (normal %) (r=−0.25, P=0.01). It was concluded that increased NO production may influence sperm production, motility and morphology in patients with varicocele.

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Received: 21 February 2000 / Accepted: 20 June 2000

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Aksoy, H., Aksoy, Y., Özbey, I. et al. The relationship between varicocele and semen nitric oxide concentrations. Urological Research 28, 357–359 (2000). https://doi.org/10.1007/s002400000132

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  • DOI: https://doi.org/10.1007/s002400000132

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