Article PDF
References
Sager R (1983) Genomic rearrangements and the origin of cancer. In: German J (ed) Chromosome mutation and neoplasia. Liss, New York, pp 333–346
Boveri T (1902) Über mehrpolige Mitosen als Mittel zur Analyse des Zellkerns. Verh Phys Med Gesellschaft Würzburg 35:67–90
Boveri T (1964) On multipolar mitosis as a means to analyse the cell nucleus. In: Willier BH, Oppenheimer J (ed) Foundations of experimental embryology. Prentice-Hall, New York (English translation of ref 2)
Surridge C (2001) Nature milestones: chromosomes to the fore http://www.nature.com/celldivision/milestones/full/milestone01.html
Boveri T (1914) Zur Frage der Entstehung maligner Tumoren. Fischer, Jena
Boveri T (1929) The origin of malignant tumors. Williams and Wilkins, Baltimore; Baillière, Tindall & Cox, London
Hansemann D von (1890) Über asymmetrische Zelltheilung in Epithelkrebsen und deren biologische Bedeutung. Virchows Arch Pathol Anat 119:299–326
Hansemann D von (1906) Über pathologische Mitosen. Virchows Arch Pathol Anat 123:356–370
Bishop JM (1995) Cancer: the rise of the genetic paradigm. Genes Dev 9:1309–1315
Anders F (1991) Contributions of the Gordon-Kosswig melanoma system to the present concept of neoplasia. Pigment Cell Res 3:7–29
Mitelman F, Johansson B, Mertens F (1998) Catalog of chromosome aberrations in cancer, 5th edn. CD-ROM version with annual updates. Wiley, New York
Anonymous (2002) Mitelman database of chromosome aberrations in cancer. Mitelman F, Johansson B, Mertens F (eds) http://cgap.nci.nih.gov/Chromosomes/Mitelman
Weber BL (2002) Cancer genomics. Cancer Cell 1:37–47
Doxsey S (2001) Re-evaluating centrosome function. Nat Rev Mol Cell Biol 2:688–698
Brinkley BR (2001) Managing the centrosome numbers game: from chaos to stability in cancer cell division. Trends Cell Biol 11:18–21
Marx J (2001) Cell biology. Do centrosome abnormalities lead to cancer? Science 292:426–429
Lengauer C, Kinzler KW, Vogelstein B (1998) Genetic instabilities in human cancers. Nature 396:643–649
Lingle WL, Barrett SL, Negron VC, D’Assoro AB, Boeneman K, Liu W, Whitehead CM, Reynolds C, Salisbury JL (2002) Centrosome amplification drives chromosomal instability in breast tumor development. Proc Natl Acad Sci USA 99:1978–1983
Reya T, Morrison SJ, Clarke MF, Weissman IL (2001) Stem cells, cancer, and cancer stem cells. Nature 414:105–111
Schwab M (ed) (2001) Encyclopedic reference of cancer. Springer, Berlin Heidelberg New York
Balmain A (2001) Cancer genetics: from Boveri and Mendel to microarrays. Nat Rev Cancer 1:77–82
Wunderlich V (2002) Krebs–von Hippokrates bis zur molekularen Medizin. Einige wichtige Etappen auf einem langen Weg. In. Ganten D, Ruckpaul K (eds) Molekularmedizinische Grundlagen von nicht-hereditären Tumorerkrankungen. Springer, Berlin Heidelberg New York, pp 405–425
Jahn I (1990) Grundzüge der Biologiegeschichte. Fischer, Jena 24. Muller HJ (1927) Arteficial transmutation of the gene. Science 66:84–87
Tyzzer EE (1916) Tumor immunity. J Cancer Res 1:125–155
Bauer KH (1928) Mutationstheorie der Geschwulstentstehung. Springer, Berlin
Nowell PC, Hungerford DA (1960) A minute chromosome in human chronic granulocytic leukemia. Science 132:1497
Loeb LA, Springgate CF, Battula N (1974) Errors in DNA replication as a basis of malignant changes. Cancer Res 34:2311–2321
Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW, Weinberg RA (1999) Creation of human tumour cells with defined genetic elements. Nature 400:464–468
Stehelin D, Varmus HE, Bishop JM, Vogt PK (1976) DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature 260:170–173
Schwab M, Alitalo K, Varmus HE, Bishop JM, George D (1983) A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells. Nature 303:497–501
Charles DR, Luce-Clausen EM (1942) The kinetics of papilloma formation in benzpyrene-treated mice. Cancer Res 2:261–263
Harris H, Miller OJ, Klein G, Worst P, Tachibana T (1969) Suppression of malignancy by cell fusion. Nature 223:363–368
Knudson AG (1971) Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 68:820–823
Stanbridge EJ, Flandermeyer RR, Daniels DW, Nelson-Rees WA (1981) Specific chromosome loss associated with the expression of tumorigenicity in human cell hybrids. Somatic Cell Genet 7:699–712
Cavenee WK, Dryja TP, Phillips RA, Benedict WF, Godbout R, Gallie, BL, Murphree AL, Strong LC, White RL (1983) Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature 305:779–784
Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TP (1986) A human segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323:643–646
Hartwell LH, Mortimer RK, Culotti J, Culotti M (1973) Genetic control of the cell cycle in yeast. V. Genetic analysis of cdc mutants. Genetics 74:267–286
Pardee AB (1974) A restriction point for control of normal animal cell proliferation. Proc Natl Acad Sci USA 71:1286–1290
Nurse P, Bisset Y (1981) Gene required for G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast. Nature 292:558–560
Evans T, Rosenthal ET, Youngblom J, Distel D, Hunt T (1983) Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell 33: 389–396
Weinert T, Hartwell L (1989) The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science 241:317–322
Mittnacht S, Weinberg RA (1991) G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment. Cell 65:381–393
Fialkow PJ, Najfeld V, Reddy AL, Singer J, Steinmann L (1978) Chronic lymphocytic leukaemia: clonal origin in a committed B-lymphocyte progenitor. Lancet 2:444–446
Foulds L (1954) Tumor progression: a review. Cancer Res 14:327–339
Nowell PC (1976) The clonal evolution of tumor cell populations. Science 194:23–28
Berenblum I (1941) The cocarcinogenic action of croton resin. Cancer Res 1:44–48
Rous P, Kidd JG (1941) Conditional neoplasms and subthreshold neoplastic states. J Exp Med 73:365–389
Deelmann HT (1922) Die Entstehung des experimentellen Teerkrebses und die Bedeutung der Zellregeneration. Z Krebsforsch 21:220–226
Armitage P, Doll R (1954) The age distribution of cancer and a multi-stage theory of carcinogenesis. Br J Cancer 8:1–12
Fukasawa K, Choi T, Kuriyama R, Rulong S, Vande Woude GF (1996) Abnormal centrosome amplification in the absence of p53. Science 271:1744–1747
Hastie ND, Dempster M, Dunlop MG, Thompson AM, Green DK, Allshire RC (1990) Telomere reduction in human colorectal carcinoma and with ageing. Nature 346:866–868
Gisselsson D, Jonson T, Petersen A, Strombeck B, Dal Cin P, Hoglund M, Mitelman F, Mertens F, Mandahl N (2001) Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors. Proc Natl Acad Sci USA 98:12683–12688
Cleaver JE (1968) Defective repair replication of DNA in xeroderma pigmentosum. Nature 218:652–656
Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, Cunha GR (1999) Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 59:5002–5011
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Wunderlich, V. JMM — Past and Present. J Mol Med 80, 545–548 (2002). https://doi.org/10.1007/s00109-002-0374-y
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00109-002-0374-y