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Schedule-Dependent Effects Of Chlordiazepoxide On Operant Behavior In Rats

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Abstract

Rats pressed a lever on either a variable interval or a fixed ratio schedule of food reinforcement. Both schedules maintained similar high overall rates of responding. A dose of 20 mg/kg of chlordiazepoxide depressed response rates on both schedules. However, the effects of lower doses (2.5, 5 mg/kg) were schedule-dependent, overall Vi response rates being increased but overall Fr response rates showing no such increase.

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Authors and Affiliations

  1. Department of Psychology, University of Birmingham, P.O. Box 363, Birmingham, B15 2TT, England

    D. J. Sanger & D. E. Blackman

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  1. D. J. Sanger
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  2. D. E. Blackman
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Additional information

This work was supported by a grant from the Medical Research Council. The chlordiazepoxide was kindly supplied by Roche Products Limited.

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Sanger, D.J., Blackman, D.E. Schedule-Dependent Effects Of Chlordiazepoxide On Operant Behavior In Rats. Psychol Rec 26, 131–134 (1976). https://doi.org/10.1007/BF03394370

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  • DOI: https://doi.org/10.1007/BF03394370

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