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Thallium-201 reinjection images can identify the viable and necrotic myocardium similarly to metabolic imaging with glucose loading18F-fluorodeoxyglucose (18FDG)-PET

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Abstract

We compared the usefulness of18F-fluorodeoxyglucose (18FDG)-PET with glucose loading and thallium-201 (201Tl) reinjection imaging for determining the viability of the myocardium in 21 patients with an old anterior myocardial infarction. We obtained transaxial views during201T1 reinjection imaging performed 10 minutes after post-exercise injection of 37 MBq201Tl. PET imaging with 75 g oral glucose loading was performed 60 min after injection of 148 MBq of I8FDG. Wall motion was evaluated by echocardiography. Excellent18FDG-PET images were obtained in 19 of 21 subjects in whom plasma glucose levels were below 251 mg/d/. The results of201Tl reinjection imaging and18FDG-PET imaging were in agreement in 20 of the 21 subjects. Echocardiography demonstrated hypokinesis or akinesis in segments identified as abnormal in imaging studies. Our results showed that201Tl reinjection imaging identified the viable and necrotic myocardium similarly to metabolic imaging obtained by18FDG-PET with glucose loading.

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Authors and Affiliations

  1. Second Department of Internal Medicine, Iwate Medical University, 19-1, Uchimaru, 020, Morioka, Japan

    Naonori Ogiu, Kenji Nakai & Katsuhiko Hiramori

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  1. Naonori Ogiu
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  2. Kenji Nakai
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  3. Katsuhiko Hiramori
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Ogiu, N., Nakai, K. & Hiramori, K. Thallium-201 reinjection images can identify the viable and necrotic myocardium similarly to metabolic imaging with glucose loading18F-fluorodeoxyglucose (18FDG)-PET. Ann Nucl Med 8, 171–176 (1994). https://doi.org/10.1007/BF03164993

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  • DOI: https://doi.org/10.1007/BF03164993

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