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Systems analysis of the integrative activity of the neuron

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Abstract

This article is aimed at revising the traditional concept of neuronal activity based on preeminence of transmembrane potentials and “electric summation” on the neuron surface. It presents a historical survey of the emergence of the prevailing concept on propagation of potentials alongconductive structures and reveals the psychological situation that determined the transfer of this concept to dendrites and the neuronal soma. Structural and biophysical properties of the neuron which do not permit information propagation along the neuronal membrane without crude distortion are critically discussed in detail.

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  1. First Moscow Sechenov Medical Institute, Moscow, USSR

    P. K. Anokhin

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  1. P. K. Anokhin
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  2. Samuel A. Corson
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Dedicated to the 250th Anniversary of the Academy of Sciences of the U.S.S.R., as a Tribute to its Multifaceted Influence on the Development of Russian and Soviet Culture.

This article was originally published in Russian as follows: USPEKHI FIZIOLICHESKIKH NAUK, Volume 5 (2), 1974. We are extremely grateful to Samuel and Elizabeth Corson for this translation. The great importance of Academician Anokhin’s work for research throughout the world should be further recognized with this publication.

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Anokhin, P.K., Corson, S.A. & Corson, E.O. Systems analysis of the integrative activity of the neuron. Pav. J. Biol. Sci. 19, 43–101 (1984). https://doi.org/10.1007/BF03003132

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