Abstract
In our hospital, 24 patients who underwent surgery for breast cancer during 1980 to 2001 were diagnosed with metastasis to the eye. Metastasis to the choroid was found most frequently, making the choroid the most common site of metastasis. A few patients had metastasis in the orbit. Decreased visual acuity and tunnel vision were frequently found in patients who had metastasis to the choroid, and ocular floaters and blurred vision were also found in a few patients. Patients with metastasis to the orbit showed diplopia caused by ocular dyskinesia and eyelid swelling. The mean postoperative period until the diagnosis with metastasis to the eye was 3 years and 2 months, with most cases diagnosed between 20 and 40 months postoperatively, a relatively long period. We performed radiotherapy in 21 of the 24 patients, and more than half of the patients showed improvement. The mean survival period after diagnosis with metastasis to the eye was 10 months, and most of them already had recurrence to other organs such as the bones or lungs. Examination with consideration of metastasis to the eyes is required to improve the quality of life of cancer patients.
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References
Yabe H: Metastatic choloidal tumor.Ganka 42:153–158,2000 (in Japanese).
Taniguchi Y, Bando H, Kawamura T, Sasabe T: Review of twelve cases of metastatic uveal tumor.Ganka Rinsho Iho 2:112–114, 2002 (in Japanese).
Kaneko A: Metastatic Breast Cancer to the Eye and Orbit.Nyuugann no Rinsho 9:31–36, 1994 (in Japanese with English abstract).
Yamada M, Ogawa T, Satou K, Juzoji H: A case of metastatic choroidal tumor from breast cancer.Ganka Rinsho Iho 10:198–205, 1992 (in Japanese).
Shien T, Doihara H, Taira N, Shimizu N: A case of Breast Cancer Metastalized to the Choroidea of the Left Eye.Rinsho Geka 64:1082–1085, 2003 (in Japanese).
Yano M, Oda I: Review of 53 cases of metastatic choroidal tumor.Rinsho Ganka 45:1347–1350, 1990 (in Japanese).
Amichetti M, Caffo O, Minatel E, Roncadin M, Valli MC, Lozza L, Panizzoni G: Ocular metastasis from breast carcinoma: A multicentric retrospective study.Oncology Reports 7:761–765, 2000.
Inoue S, Nagahori K, Yamada H, Itakura J, Matsumoto Y: Two Cases of Choroidal Metastasis from Breast Cancer.Breast Cancer 3:75–78, 1996.
Merrill CF, Kaufman DI, Dimitrov NV: Breast Cancer Metastatic to the Eye Is a Common Entity.Cancer 68:623–627, 1991.
Shields JA: Diagnosis and management of intraocular tumors. CV Mosby, St Louis, pp278–321, 1983.
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Tamura, M., Tada, T., Tsuji, H. et al. Clinical study on the metastasis to the eyes from breast cancer. Breast Cancer 11, 65–68 (2004). https://doi.org/10.1007/BF02968005
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DOI: https://doi.org/10.1007/BF02968005