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Mitochondria can power cells to life and death

Role of mitochondria in apoptosis

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Conclusion

Mitochondria serve as power houses of cells but they also possess ‘covered’ knives to kill the cells. A number of intrinsic and extrinsic factors exist which regulate cell killing by mitochondria. Caspases are comparable to a surgeon’s knife, which can be used to sculpt organisms, get rid of wayward, redundant and incorrigibly damaged cells, but can spell doom if not controlled properly.

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Authors and Affiliations

  1. Eukaryotic Gene Expression Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, 110 067, New Delhi, India

    Nand K. Sah, Tarvinder K. Taneja & Seyed E. Hasnain

  2. Laboratory of Molecular & Cellular Biology, CDFD, CDFD Interim Building Complex 7-18, E & F, Nacharam, 500 076, Hyderabad, India

    Seyed E. Hasnain

  3. Department of Medical Elementology & Toxicology, Jamia Hamdard, Hamdard Nagar, 110 062, New Delhi, India

    Tarvinder K. Taneja

Authors
  1. Nand K. Sah
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  2. Tarvinder K. Taneja
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  3. Seyed E. Hasnain
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Correspondence to Seyed E. Hasnain.

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Sah, N.K., Taneja, T.K. & Hasnain, S.E. Mitochondria can power cells to life and death. Reson 5, 74–84 (2000). https://doi.org/10.1007/BF02837908

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  • DOI: https://doi.org/10.1007/BF02837908

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