Skip to main content
Log in

Optimal design in average for inference in generalized linear models

  • Articles
  • Published:
Statistical Papers Aims and scope Submit manuscript

Abstract

This paper considers the problem of optimal design for inference in Generalized Linear Models, when prior information about the parameters is available. The general theory of optimum design usually requires knowledge of the parameter values. These are usually unknown and optimal design can, therefore, not be used in practice. However, one way to circumvent this problem is through so-called “optimal design in average”, or shortly, “ave optimal”. The ave optimal design is chosen to minimize the expected value of some criterion function over a prior distribution. We focus our interest on the aveD A-optimality, including aveD- and avec-optimality and show the appropriate equivalence theorems for these optimality criterions, which give necessary conditions for an optimal design. Ave optimal designs are of interest when e.g. a factorial experiment with a binary or a Poisson response in to be conducted. The results are applied to factorial experiments, including a control group experiment and a 2×2 experiment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Arnoldsson, G. (1996-1). Optimal allocation for linear combinations of linear predictors in generalized linear models,Journal of Applied Statistics, Vol.23, 5, 493–505.

    Article  MathSciNet  Google Scholar 

  • Arnoldsson, G. (1996-2).Optimal Design for Inference in Generalized Linear Models, Statistical studies, No. 22, Department of Statistics, University of Umeå, Sweden.

    Google Scholar 

  • Atkinson, A.C. and Donev, D.L. (1992).Optimum Experimental Design, Oxford University Press.

  • Chaloner, K. and Larntz, K. (1989). Optimal Bayesian Design Applied to Logistic Regression Experiments.Journal of Statistical Planning and Inference,21:191–208.

    Article  MATH  MathSciNet  Google Scholar 

  • Fedorov, V.V. (1972).Theory of Optimal Experiments, Academic Press, New York.

    Google Scholar 

  • Fedorov, V. and Hackl, P. (1997).Model-oriented Design of Experiments, Springer, New York.

    MATH  Google Scholar 

  • McCullagh, P. and Nelder, J. (1989).Generalized Linear Models, Chapman & Hall, London, 2nd edition.

    MATH  Google Scholar 

  • Pazman, A. (1986).Foundation of Optimum Experimental Design, D. Reidel Publishing Company, Dohrdrecht.

    Google Scholar 

  • Pettersson, H. (2001)Optimum in Average and Minimax Designs for Estimation of Generalized Linear Models, Statistical Studies, No. 26, Department of Statistics, University of Umeå, Sweden.

    Google Scholar 

  • Pettersson, H. and Nyquist, H. (2003). Computation of Optimum in Average Designs for Experiments with Finite Design Space,Communications in Statistics—Simulation and computation, Resubmitted and accepted, to be published in Volume 32, Issue 1.

  • Pukelsheim, F. (1993).Optimal Design of Experiments, Wiley, New York.

    MATH  Google Scholar 

  • Silvey, S.D. (1980).Optimal Design, Chapman & Hall, London.

    MATH  Google Scholar 

  • Sitter, R.R. and Torsney, B. (1995). D-optimal designs for generalized linear models. In C.P. Kitsos and W.G. Muller, editors,Proceedings of MODA4, p. 87–102. Physica Verlag, Heidelberg.

    Google Scholar 

  • Wynn, H.P. (1970). The sequential generation of D-optimal experimental designs.Annals of Mathematical Statistics,41:1655–1664.

    Article  MathSciNet  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hans Pettersson.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pettersson, H. Optimal design in average for inference in generalized linear models. Statistical Papers 46, 79–99 (2005). https://doi.org/10.1007/BF02762036

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02762036

Keywords

Navigation