Abstract
Fetal vascular disruptions can cause specific patterns of birth depending on the location, extent and timing of the disruptive event in the embryonic life. An example of this is subclavian artery supply disruption sequence occurring around 6 weeks of gestation which causes various combinations of Poland, Klippel-Feil and Mobius anomalies. A one-month-old child with features of all three anomalies alongwith other associated features is described here.
References
Van Allen MI. Fetal vascular disruptions: Mechanisms and some resulting birth defects.Pediatr Ann 1981; 10: 219–233.
Brill CB, Peyster RK, Keller MS, Galtman L. Isolation of the right subclavian artery with subclavian steal in a child with Klippel-Feil anomaly: An example of subclavian artery supply disruption sequence.Am J Med Genet 1987; 26: 933–940.
Bavnick JNB, Weaver DD. Subclavian artery supply disruption sequence: Hypothesis of a vascular etiology for Poland, klippel-Feil, and Mobius anomalies.Am J Med Genet 1986; 23: 903–918.
McGillivray BC, Lowry RB. Poland syndrome in British Columbia: Incidence and reproductive experience of affected persons.Am J Med Genet 1977; 1: 65–74.
Bardeen CR, Lewis WH. Development of limbs and body wall and back in man.Am J Anat 1901; 1: 1–36.
Winter RB, Moe JH, Lovstein JE. The incidence of Klippel-Feil syndrome in patients with congenital scoliosis and kyphosis.Spine 1984; 9: 363–366.
Jones KL.Smith’s Recognizable Patterns of Human Malformation. 5th edn. Philadelphia. WB Saunders, 1997; 618.
Widgreow AD. Klippel-Feil anomaly, cleft palate, and bifid tongue.Ann Plast Surg 1990; 25: 216–222.
Thompson E, Hand E, Sheffield L. Autosomal dominant Klippel-Feil anomaly with cleft palate.Clin Dysmorphol 1998; 7: 11–15.
Kumar D. Mobius syndrome.J Med Genet 1990; 27: 122–126.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Issaivanan, M., Virdi, V.S. & Parmar, V.R. Subclavian artery supply disruption sequence—Klippel-Feil and Mobius anomalies. Indian J Pediatr 69, 441–442 (2002). https://doi.org/10.1007/BF02722639
Issue Date:
DOI: https://doi.org/10.1007/BF02722639