Abstract
The effects of exposing seawater adapted cichlid fish, tilapia(Sarotherodon mossambicus Peters) to sublethal concentrations of toluene on the activities of lactate dehydrogenase, succinate dehydrogenase and acetylcholinesterase were studied. The activity of lactate dehydrogenase increased while those of succinate dehydrogenase and acetylcholinesterase were inhibited in most tissues of the exposed fish. The alterations in the dehydrogenases suggested that some changes in carbohydrate metabolism may have occurred. Acetylcholinesterase inhibition in brain and other tissues indicated impairment of nervous function in toluene-intoxicated tilapia.
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References
American Public Health Association, American Water Works Association and Water Pollution Control Federation (1971)Standard methods for the examination of water and waste water, 13th ed. New York APHA Inc.
Anderson, J.W., Neff, J. M., Cox, B.A., Tatem, H. E.and Hightower, G. M. (l974)Mar. Biol.,27, 75.
Berry, W. O. (1980)Environ. Pollut.,21, 109.
Coppage, D. L. (1972)Trans. Am. Fish Soc.,101, 534.
Dange, A. D. (1979)Some effects of petroleum hydrocarbons on aquatic organisms, Ph. D. Thesis, University of Bombay, Bombay.
DiMichele, L. and Taylor, M. H. (1978)J. Fish. Res. Board Can.,35, 1060.
Gardner, G. R. (1975) inThe pathology of fishes (eds) W. E. Ribelin and G. Miyaki, (Wisconsin: University of Wisconsin Press) p. 657.
Gerarde, H. W. (1960)Toxicology and biochemistry of aromatic hydrocarbons (New York, Elsevier Publ. Co.)
Hodson, P. V. (1976)J. Fish. Res. Board Can.,33, 1393.
Korn, S., Hirsch, N. and Struhsaker, J. (1977)U.S. Natl. Mar. Ser. Fish Bull.,75, 633.
Kutty, K. M., Chandra, R. K. and Shakti Chandra (1976)Experientia,32, 289.
Levitan, W. M. and Taylor, M. H. (1979)J. Fish. Res. Board Can.,36, 615.
Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. (1951)J. Biol. Chem.,193, 265.
Mansuri, A. P. and Pandya, C. H. (1977)J. Anim. Morphol. Physiol.,24, 47.
Meenakshi, S., Rajamanickam, C. and Jayaraman, J. (1979)J. Biosci.,1, 427.
Nachlas, M. N., Margulies, S. P. and Seligman, A. M. (1960)J. Biol. Chem.,235, 2739.
Nicholson, H. P. (1967)Science,158, 871.
Pickering, Q. H. and Henderson, C. (1966)J. Water Pollut. Cont. Fed.,38, 1419.
Pilz, W. (1965) inMethods of enzymatic analysis (ed) H. U. Bergmeyer, (New York: Academic Press) p. 765.
Spiegel, M. R. (1961)Outline of theory and problems of statistics, (New York: Schaum Publ. Co.).
Srikantan, T. N. and Krishnamurthy, C. R. (1955)J. Sci. Ind. Res.,14, 206.
Stoss, F. W. and Haines, T. A. (1979)Environ. Pollut.,20, 139.
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Dange, A.D., Masurekar, V.B. Toluene toxicity: Effects of sublethal levels on enzyme activities in seawater adapted tilapia(Sarotherodon mossambicus Peters). J Biosci 3, 129–134 (1981). https://doi.org/10.1007/BF02702655
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DOI: https://doi.org/10.1007/BF02702655