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Fibreoptic bronchoscopy for early diagnosis of bronchogenic carcinoma: A comparison of yield of biopsy, bronchial lavage and brush biopsy

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Abstract

Fifty-one patients with endoscopically visible bronchogenic carcinoma underwent fibreoptic bronchoscopy. At the same sitting, bronchial brush cytology was taken followed by collection of bronchial washings after lavage with 10 ml of 0.9 per cent saline. Three specimens of bronchial tissue were taken from different sites of a tumour. Bronchial biopsy, was found to be the most sensitive procedure as it was positive in 36 (70.5%) patients as compared to bronchial was (64.7%) and brush cytology (55%). Bronchial lavage alone was positive in five and only brush cytology was contributory in four. Massive bleeding was encountered in three patients and one of them required urgent blood transfusion. There was no mortality.

It is concluded that the diagnostic yield of endoscopy procedures is enhanced by combining all the three techniques simultaneously

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Sarkar, S.K., Joshi, N., Purohit, S.D. et al. Fibreoptic bronchoscopy for early diagnosis of bronchogenic carcinoma: A comparison of yield of biopsy, bronchial lavage and brush biopsy. Indian J Thorac Cardiovasc Surg 6, 68–70 (1989). https://doi.org/10.1007/BF02664030

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