Summary
A method for the performance testing of Sedex 55 Evaporative Light Scattering Detectors (ELSD) has been developed as part of our regulatory compliance programme. The method uses a readily available chromatographic column, caffeine as the test probe and can be completed in less than one hour.
Similar content being viewed by others
References
Furman, W.B.; Layloff, T.P.; Tetzlaff, R.F.Journal of AOAC International 1994,77 1314.
Guideline for the Qualification of an Automated UV detector Based HPLC system. Waters Millipore1993.
Lafosse, M.; Elfakir, C.; Morin-Allory L.; Dreux, M..J. High Resol. Chromatog. 1992,15, 312.
Kibbey, C.E.Molecular Diversity 1995,1, 247.
Porter, R.S.; Chen, T.K..J. Chromatogr. 1996,730, 399.
Bedson, P.Accred. Qual. Assur. 1996,1, 265–274.
Cebolla, V.L.; Membrado, L.; Vela, J.; Ferrando, A.C.Seminars in Food Analysis 1997,2, 171.
Vial, J.; Jardy, A.Anal. Chem. 1999,71, 2672.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sims, J.L. Proposed performance qualification and calibration method for evaporative light scattering detectors. Chromatographia 53, 401–404 (2001). https://doi.org/10.1007/BF02491074
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02491074