Abstract
We developed a continuous oxygen consumption (Vo2) measurement system employed the reversed Fick method, in which Vo2 in computed from continuously measured sured arterial and mixed venous oxygen saturation assed by pulse oximetry and mixed venous oximetry, respectively, and cardiac output by the heat deprivation technique. This system was compared with the conventional intermittent reversed fick method in 7 patients during surgery and with indirect calorimetry in 4 intensive care unit (ICU) patients. The Vo2 measured by the continuous reversed Fick method showed a high correlation with those simultaneously measured by the intermittent Fick method (r=0.97,P<0.01) and by indirect calorimetry (r=0.74,P<0.01). The 95% confidence limits (bias±2 SD) of the continuous reversed Fick method were −0.6±45 ml·min−1 with the intermittent Fick method and −31±56 ml·min−1 with indirect calorimetry. The continuous Fick method is in satisfactory agreement with the conventional methods for the measured of Vo2 and potentially allows for convenient assessment of Vo2 in critically ill patients.
Similar content being viewed by others
References
Schumacker PT, Cain SM (1987) The concept of a critical oxygen delivery. Intensive Care Med 13:223–229
Shoemaker WC (1987) Circulatory mechanisms of shock and their mediators. Crit Care Med 15:787–794
Shoemaker WC, Appel PL, Kram HB (1988) Tissue oxygen debt as a determinant of lethal and non-lethal postoperative organ failure. Crit Care Med 19:147–149
Villar J, Slutsky AS, Hew E, Aberman A (1990) Oxygen transport and oxygen consumption in critically ill patients. Chest 98:678–692
Weissman C, Kemper M (1991) The oxygen uptake oxygen delivery relationship during ICU interventions. Chest 99:430–435
Rivers EP, Wortsman J, Rady MY, Blake HC, McGeorge FT, Bunderer NM (1994) The effect of the total cumulative epinephrine does administeired during human CPR on hemodynamic, oxygen transport, and utilization variables in the postesuscitation period. Chest 106:1499–1507
Behrendt W, Weiland C, Kalff J, Giani G (1987) Continuous measurement of oxygen uptake: evaluation of the Engstrom metabolic computer and clinical experiences. Acta Anaesthesiol Scand 31:10–14
Takara J, Keinanen O, Vaisanen P, Kari A (1989) Measurement of gas exchange in intensive care: Laboratory and clinical validation of a new device. Crit Care Med 17:1041–1047
Smithies MN, Royston B, Makita K, Konieiczko K, Nunn JF (1991) Comparison of oxygen consumption measurements: Indirect calorimetry versus the reversed Fick method. Crit Care Med 19:1401–1406
Makita K, Nunn JF, Royston B (1990) Evaluation of metabolic measurement instruments for use in critically ill patients. Crit Care Med 18:638–644
Baumann R, Bratels H, Bauer C (1987) Blood oxygen transport. In: Fishman AP (ed). Handbook of physiology, sect 3, vol 4. American Physiological Society, Bethesda, pp 147–172
Miyasaka K, Volgyesi G, Katrayama M, Tanabe S (1991) Continuous cardiac output determination by thermodeprivation. J Anesth 5:205–212
Pinsky MR (1990) The meaning of cardiac output Intensive Care Med 16:415–417
Light RB (1988) Intrapulmonary oxygen consumption in experimental pneumococcal pneumonia. J Appl Physiol 64:2490–2495
Rouby JJ, Poete P, Bodin L, Bourgeois J, Pharm MA, Viars P (1990) Three mixed venous saturation catheters in patients with circulatory shock and respiratory failure. Chest 98:954–958
Reinhart K, Moser N, Rudolph T, Bredle K, Specht M, Gramm HJ, Goecke J, Eyrich K (1988) Accuracy of two mixed venous saturation catheters during long term use in critically ill patients. Anesthesiology 69:769–773
Hannhart B, Haberer JP, Saunier C, Laxenaire MC (1991) Accuracy and precision of fourteen pulse oximeters. Eur Respir J 4:115–119
Author information
Authors and Affiliations
Additional information
This study was supported in part by Grants-in-Aid for the Encouragement of Young Scientists 01771185 and 04857171 from the Ministry of Education, Science and Culture of Japan
About this article
Cite this article
Fukui, M., Imoto, M., Shime, N. et al. Continuous measurement of oxygen consumption using the reversed fick method. J Anesth 11, 27–31 (1997). https://doi.org/10.1007/BF02480001
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02480001