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In vitro activity of trimethoprim againstBorrelia burgdorferi

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Abstract

A new culture medium has been developed to evaluate the activity of trimethoprim and sulfamethoxazole againstBorrelia burgdorferi in vitro. In this specially modified Barbour-Stoenner-Kelly medium, in which antagonizing substances were reduced to a minimum, trimethoprim was more active againstBorrelia burgdorferi than against a sensitive strain ofEscherichia coli, but sulfamethoxazole was not active againstBorrelia burgdorferi.

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Authors and Affiliations

  1. Division of Infectious Diseases, Department of Medicine, Karl-Franzens University, Auenbruggerplatz 15, A-8036, Graz, Austria

    E. C. Reisinger, I. Wendelin & R. Gasser

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  1. E. C. Reisinger
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  2. I. Wendelin
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  3. R. Gasser
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Reisinger, E.C., Wendelin, I. & Gasser, R. In vitro activity of trimethoprim againstBorrelia burgdorferi . Eur. J. Clin. Microbiol. Infect. Dis. 16, 458–460 (1997). https://doi.org/10.1007/BF02471911

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  • DOI: https://doi.org/10.1007/BF02471911

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