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Scintiscanning demonstration of thymoma: Comparative study on scintiscans using201Tl,67Ga and75Se

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Abstract

Thymus scintigraphy was performed using201Tl-chloride,67-Ga-citrate and75Se-selenomethionine on 30 thymoma patients with or without myasthenia gravis. Mass negativity was observed in 6 out of 17 (35.3 per cent) and 3 out of 13 cases (23.1 per cent), respectively. A rate of 70 per cent (21 cases out of 30) of mass positivity was observed by thymus scan using201Tl. With regard to the relation between thymus scan and cell type,201Tl-scan exhibited a high rate of mass positivity, regardless of the cell type while the75Sescan showed a trend toward mass positivity in epithelial cell predominant cases. With201Tl, mass positivity was observed when the CPM/g ratio for tumors and blood exceeded 3.0. This trend can serve as an index for the suitability of supplementary chemo- and radiotherapies, as well as for prognosis in cases of relapse, and in those for whom excision was not complete.

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Yuzuriha, H., Morimoto, M., Inokawa, K. et al. Scintiscanning demonstration of thymoma: Comparative study on scintiscans using201Tl,67Ga and75Se. The Japanese Journal of Surgery 16, 250–256 (1986). https://doi.org/10.1007/BF02470933

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