Abstract
An extract of garlic powder in isotonic phosphate buffer and adjoen (bioactive compound isolated from garlic powder) suppress human blood platelet aggregation induced by ADP and arachidonic acidin vitro. Adjoen more effectively than aspirin inhibits ADP-induced platelet aggregation but is inferior to aspirin if platelet aggregation is induced by arachidonic acid.Ex vivo oral intake of one Allicor tablet significantly decreases rabbit platelet aggregation induced with ADP. It is suggested that long-acting garlic powder tablets prevent thromboembolic complications and are recommended for correcting hemostasis parameters in patients with atherosclerotic involvement of blood vessels.
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 7, pp. 79–100, July, 1997
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Andrianova, I.V., Gabbasov, Z.A., Ionova, V.G. et al. Effect of allicor on platelet aggregationin vitro andex vivo . Bull Exp Biol Med 124, 706–708 (1997). https://doi.org/10.1007/BF02445068
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DOI: https://doi.org/10.1007/BF02445068