Abstract
The reference value of L2-4 bone mineral density (BMD) was calculated in Japanese population by using cross-calibration formulae among the different types of dual energy X-ray absorptiometry (DEXA) and dual photon absorptiometry (DPA).
The scan data of lumbar spine were collected from 16 institutes equipped 3 types of DEXA and 3 types of DPA. After subtraction of inadequate scan data, a total of 1038 cases (376 males and 662 females) were accepted to be a representative “normal” population of Japanese. The L2-4 BMD values were adjusted to one equipment by using cross-calibration equations. There were significant decrease in L2-4 BMD in both sexes at age of seventies or more (9.5% decrease in males and 27.5% in females from the peak bone density).
When the cut-off value of L2-4 BMD set to 0.8 g/cm2 (QDR), 0.88 (DPX) and 0.77 (XR), 80% of correct discrimination between “normal” and osteoporotics was achieved in the forties and the fifties. Therefore, these values can utilize to diagnose early bone loss. There was significant correlation between L2-4 BMD value and the total score of criteria for involutional osteoporosis.
In summary, the BMD values obtained by cross-calibration in the different equipments might be acceptable for the reference value of Japanese population as well as for the detection of early bone loss, tentatively.
Further investigations are currently undergoing.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Orimo, H.: Epidemiology of fracture in Asia. Oral presentation at third international symposium on osteoporosis. Copenhagen Denmark, 1990.
Morita, R., Fukunaga, M., Shiraki, M., Orimo, H., Nakamura, T., Fujita, T., Inoue, T., Kaneda, K., Tomita, A., Yamamoto, K and Norimatsu, H.: Cross calibration of BMD values among the different bone densitometric equipments. Abstract of third international symposium on osteoporosis, p83, 1990.
Mazess, R.B. and Barden, H.S.: Bone densitometry for diagnosis and monitoring osteoporosis. Proc. Soc. Exp. Biol. Med. 191: 261–271, 1989.
Norimatsu, H., Mori, S., Uesato, T., Yoshikawa, T. and Katsuyama, N.: Bone mineral density of the spine and proximal femur in normal and osteoporotic subjects in Japan. Bone Miner. 5: 213–222, 1989.
Ribot, C., Tremollieres, F., Pouilles, J.M., Louvet, J.P. and Guiraud, R.: Influence of the menopause and aging on spinal density in French women. Bone Miner. 5: 89–97, 1990.
Klaushofer, K., Kalchhauser, G., Findl, I., Urbanek, A. and Koller, K.: Spine and femur density using dual energy X-ray absorptiometry (DEXA) in normal Austrian women. Abstract of third international symposium on osteoporosis p91, 1990.
Szejnfeld, V.L., Aldrighi, J.M., Ferraz, M.B. and Atra, E.: Spine and femur density using dual photon absorptiometry in Brazilian white women. Ibid p19, 1990.
Arriagada, M., Arinoviche, R., Numhauser, M., Portilla, P. and Escobar, A.L.: BMD in a normal Caucasian Chilean female population. Ibid p65, 1990.
Author information
Authors and Affiliations
About this article
Cite this article
Shiraki, M., Fukunaga, M., Morita, R. et al. Cross calibrated standard values of vertebral bone mineral density in Japanese. J Bone Miner Metab 9 (Suppl 1), 44–49 (1991). https://doi.org/10.1007/BF02375933
Issue Date:
DOI: https://doi.org/10.1007/BF02375933