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Gastric emptying following Finney pyloroplasty and vagotomy

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Abstract

Gastric emptying was evaluated in a series of unanesthetized dogs in the intact state, following Finney pyloroplasty, and with the addition of vagotomy. Sodium chromate labeled test meals of glucose, trisodium citrate, and trisodium citrate-fat were used. Finney pyloroplasty resulted in a trend for delayed emptying of fat from the stomach. The trisodium citrate test meal increased the levels of gastric secretion after pyloroplasty.

Association of our previous motility data based on pyloroplasty studies with the current gastric-emptying evaluations indicate that too large a stoma between the antrum and duodenum is an impediment to normal gastric emptying of fatty meals.

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Authors and Affiliations

  1. Pharmacology Department, Medical and Scientific Affairs Division, Parke, Davis & Co., Ann Arbor, Mich

    Jack R. Ludwick MD, James N. Wiley & Paul Bass PhD

  2. Department of Surgery, University of Michigan Medical Center, 48104, Ann Arbor, Mich

    Jack R. Ludwick MD, James N. Wiley & Paul Bass PhD

Authors
  1. Jack R. Ludwick MD
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  2. James N. Wiley
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  3. Paul Bass PhD
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Additional information

The authors appreciate the technical assistance of Mr. James E. Copp, Department of Biostatics, Parke, Davis Research Labs.

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Ludwick, J.R., Wiley, J.N. & Bass, P. Gastric emptying following Finney pyloroplasty and vagotomy. Digest Dis Sci 15, 347–352 (1970). https://doi.org/10.1007/BF02239291

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  • DOI: https://doi.org/10.1007/BF02239291

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