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Observation on the capping of spleen lymphocytes from scrapie infected mice after treatment with anti Ig

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Abstract

Staining of lymphocytes from scrapie-infected STU mice with FITC-labelled anti-mouse Ig revealed disturbances in the capping process when compared with lymphocytes from mock-infected animals. Quantitative evaluation indicates that 10–15% of cells from scrapie-infected animals show an altered capping behaviour.

These phenomena are discussed with special reference to the role of the lymphoreticular system in early scrapie agent replication.

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Vettermann, W., Werner, H.J., Schmeißer, S. et al. Observation on the capping of spleen lymphocytes from scrapie infected mice after treatment with anti Ig. Med Microbiol Immunol 169, 75–81 (1981). https://doi.org/10.1007/BF02171774

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  • DOI: https://doi.org/10.1007/BF02171774

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