Summary
The disappearance of thrombin—formed in the blood, or added to serum-follows a manomolecular reaction-type. Heparin increases the reaction-velocity of this thrombin-inactivating process.
Our investigation established that toluidine blue or kinase, which, according to the literature, bind heparin, strongly reduce the speed of thrombin-inactivation too. Therefore the heparin-binding capacity of these substances is also manifested in the decrease of thrombin-inactivation.
Literatur
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M. Gerendás, Hung. acta physiol.,1, 97 (1947).
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Horn, Z., Gerendás, M. & Borsodi, L. Die Wirkung des Toluidinblaus und der Thrombokinase auf den Vorgang der Thrombininaktivierung. Experientia 4, 402–403 (1948). https://doi.org/10.1007/BF02145206
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DOI: https://doi.org/10.1007/BF02145206