Summary
This study investigated the prevalence ofBrucella antibodies in the general population in two regions in southern Italy. A total of 1,294 subjects were recruited from January to June 1996 among patients attending randomly selected public and private laboratories and pediatric outpatient clinics. Information on sex, age, residence, and occupation was recorded. Seroprevalence of brucellosis was studied by the safranin O-stained antigen microagglutination test. The chi-square test and multiple logistic regression were performed. An overall prevalence of brucellosis of 3.1% was recorded; no significant difference was found between the two regions, with values of 2.7% in Campania and 3.8% in Calabria. Multiple logistic regression analysis indicated that positivity to brucellosis was significantly associated with the province the subjects reside in, ranging from 0 in Salerno to 6.2% in Caserta, and that it significantly increased with age, ranging from 1% in persons under 16 to 4.2% in those over 65 (OR=1.7; 95% CI=1.04–2.6), whereas it was not significantly associated with sex. When analysis was conducted after restriction to subjects reporting to be working, occupation was found not to be significantly associated with brucellosis. Since the spread of the disease is still of concern, though circulation ofBrucella is decreasing, strict application of measures for the eradication of brucellosis from livestock, pasteurization of milk and dairy products, and education regarding eating habits must be pursued.
Similar content being viewed by others
References
Kaufmann, A. F., Wenger, J. D.: Brucellosis. In:Last, J. M., Wallace, R. B.: Public health and preventive medicine; 13th ed. Appleton and Lange, Norwalk, CT 1992, pp. 263–264.
Young, E. J. An overview of human brucellosis. Clin. Infect. Dis. 21 (1995) 283–290.
Taylor, J. P., Perdue, J. N. The changing epidemiology of human brucellosis in Texas, 1977–1986. Am. J. Epidemiol. 130 (1989) 160–165.
Chomel, B. B., DeBess, E. E., Mangiamele, D. M., Reilly, K. F., Farver, T. B., Sun, R. K., Barrett, L. R. Changing trends in the epidemiology of human brucellosis in California from 1973 to 1992: a shift toward foodborne transmission. J. Infect. Dis. 170 (1994) 1216–1223.
Ortona, L., Cauda, R., Ventura, G., Tumbarello, M., Ballada, D., Branca, G. Ten years of brucellosis in Italy (1977–1986). Eur. J. Epidemiol. 4 (1988) 503–505.
Guerra, M., Tasselli, E., Fantini, M. G., Picotto, P. La brucellosi in Italia fra il 1981 ed il 1992. Rivista Italiana di Igiene 53 (1993) 298–321.
Decreto Ministero della Sanità no. 84/91. Regolamento per la bonifica sanitaria degli allevamenti bufalini dalla brucellosi. G. U. n. 64 Serie Generale, Rome 16.3.1991.
Decreto Ministero della Sanità no. 453/92. Regolamento concernente il piano nazionale per la eradicazione della brucellosi negli allevamenti ovini e caprini. G. U. n. 276 Serie Generale, Rome 23.11.1992.
Decreto Ministero della Sanità no. 651/94. Regolamento concernente il piano nazionale per la eradicazione della brucellosi negli allevamenti bovini. G. U. n. 277 Serie Generale, Rome 26.11.1994.
Palombino, R., Palumbo, F., Petti, A., Tagliaferro, S., Mantovani, A., Scorziello, M. The control of human brucellosis in the Campania region: an updating of knowledge and results obtained by the third year of the programme activities. Ann. Ist. Super. Sanità 28 (1992) 511–519.
Brown, S. L., Klein, G. C., McKinney, F. T., Jones, W. L. Safranin O-stained antigen microagglutination test for detection ofBrucella antibodies. J. Clin. Microbiol. 13 (1981) 398–400.
Stata Corporation: Stata Reference Manual; release 3.1. 16th ed. College Station 1993.
Montanaro, D., Romano, F., Macrì, A. Prevalenza di anticorpi anti-Brucella in popolazione sana della Campania e della Calabria. Ig. Mod. 82 (1984) 386–391.
Montanaro, D., Romano, F., Ribera, G., Del Prete, U. Brucellosis in southern Italy. A seroepidemiological survey. Giorn. Ig. Med. Prev. 29 (1988) 181–187.
Arnow, P. M., Smaron, M., Ormiste, V. Brucellosis in a group of travelers to Spain. JAMA 251 (1984) 505–507.
Brucellosis associated with unpasteurized milk products abroad. United Kingdom. Wkly. Epidemiol. Rec. 43 (1995) 308–309.
Sixl, W., Reinthaler, F., Sixl-Voigt, B., Withalm, H., Stunzner, D., Schneeweiss, W. D., Rosegger, H., Schuhmann, G., Mascher, F. Brucellosis in the upper Nile region — Melut district, Sudan. Geogr. Med. (Suppl. 1) (1988) 71–76.
Hossain A., Bakir, T. F., Chowdhury, M. N., Kurstake, E. Seroepidemiology of enteric fever and brucellosis in a developing country. J. Hyg. Epidemiol. Microbiol. Immunol. 35 (1991) 325–335.
Alballa, S. R. Epidemiology of human brucellosis in southern Saudi Arabia. J. Trop. Med. Hyg. 98 (1995) 185–189.
Ndyabahinduka, D. G., Chu, I. H. Brucellosis in Uganda. Int. J. Zoonoses 11 (1984) 59–64.
Sixl, W., Rosegger, H., Schneeweiss, H., Withalm, H., Schuhmann, G. Serological investigation in Nigeria for anthropozoonoses in human sera: brucellosis, echinococcosis, toxoplasmosis, chlamydial diseases, listeriosis, rickettsiosis. J. Hyg. Epidemiol. Microbiol. Immunol. 31 (Suppl. 4) (1987) 493–495.
Statistiche della Sanità 1993. Annuario n. 9. ISTAT, Rome 1996.
Dajani, Y. F., Masoud, A. A., Barakat, H. F. Epidemiology and diagnosis of human brucellosis in Jordan. J. Trop. Med. Hyg. 92 (1989) 209–214.
Slater, P. E., Costin, C., Seidenbaum, M., Ever-Hadani, S. Epidemiology of human brucellosis in Israel. Public Health Rev. 18 (1990/91) 159–169.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Torre, I., Ribera, G., Pavia, M. et al. A seroepidemiologic survey on Brucellosis antibodies in southern Italy. Infection 25, 150–153 (1997). https://doi.org/10.1007/BF02113602
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02113602