Abstract
InEscherichia coli, several terminal reductases catalyze the reduction of S- and N-oxide compounds. We have used mutants missing either the constitutive dimethylsulfoxide (DMSO) reductase,dmsABC, and/or the inducible trimethylamine N-oxide (TMAO) reductase,torA, to define the roles of each reductase. These studies indicated that the constitutive DMSO reductase can sustain growth on DMSO, TMAO, methionine sulfoxide (MetSO), and other N-oxide compounds. Only one inducible TMAO reductase is expressed inE. coli, and this enzyme sustains growth on TMAO but not DMSO or MetSO. Characterization of atorA −, dms−double mutant revealed that adenosine N-oxide (ANO) reductase is specifically required for anaerobic respiration on ANO in this mutant.
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Sambasivarao, D., Weiner, J.H. Differentiation of the multiple S- and N-oxide-reducing activities ofEscherichia coli . Current Microbiology 23, 105–110 (1991). https://doi.org/10.1007/BF02092258
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DOI: https://doi.org/10.1007/BF02092258